T
Thomas D. Petes
Researcher at Duke University
Publications - 197
Citations - 17517
Thomas D. Petes is an academic researcher from Duke University. The author has contributed to research in topics: Saccharomyces cerevisiae & Homologous recombination. The author has an hindex of 74, co-authored 194 publications receiving 16935 citations. Previous affiliations of Thomas D. Petes include Saint Petersburg State University & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Genetic Evidence for Preferential Strand Transfer during Meiotic Recombination in Yeast
Dilip K. Nag,Thomas D. Petes +1 more
TL;DR: It is presented genetic evidence that the nontranscribed strand is donated more frequently than the transcribed strand in spores that have an unrepaired mismatch at the HIS4 locus.
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Genetic Control of Genomic Alterations Induced in Yeast by Interstitial Telomeric Sequences.
Anthony Moore,Margaret Dominska,Patricia W. Greenwell,Anna Y. Aksenova,Sergei M. Mirkin,Thomas D. Petes,Thomas D. Petes +6 more
TL;DR: It is shown that the terminal inversions occur by the single-strand annealing pathway of DNA repair following the formation of a double-stranded DNA break within the ITS, and the point mutations induced by the ITS require the error-prone DNA polymerase ζ.
Journal ArticleDOI
Genome Instability Induced by Low Levels of Replicative DNA Polymerases in Yeast.
Dao-Qiong Zheng,Thomas D. Petes +1 more
TL;DR: In this review, the methods used to monitor genome instability in yeast are summarized, and how this analysis contributes to understanding the linkage between genome instability and DNA replication stress are summarized.
Journal ArticleDOI
Reciprocal uniparental disomy in yeast
TL;DR: A previously undescribed mode of chromosome segregation in Saccharomyces cerevisiae is reported in which one cell division produces daughter cells with reciprocal UPD for the same pair of chromosomes without an aneuploid intermediate, mimicking a meiotic chromosome segregation pattern.
Journal ArticleDOI
Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases.
Yang Sui,Lei Qi,Lei Qi,Ke Zhang,Natalie Saini,Leszek J. Klimczak,Cynthia J. Sakofsky,Dmitry A. Gordenin,Thomas D. Petes,Dao-Qiong Zheng,Dao-Qiong Zheng +10 more
TL;DR: It is suggested that single-stranded regions in yeast Saccharomyces cerevisiae are fragile, generating the DNA breaks that initiate translocations and other types of chromosome rearrangements.