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Thomas Ilg

Researcher at Max Planck Society

Publications -  66
Citations -  3316

Thomas Ilg is an academic researcher from Max Planck Society. The author has contributed to research in topics: Leishmania mexicana & Lipophosphoglycan. The author has an hindex of 35, co-authored 66 publications receiving 3159 citations. Previous affiliations of Thomas Ilg include University of Melbourne & Walter and Eliza Hall Institute of Medical Research.

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Transmission of cutaneous leishmaniasis by sand flies is enhanced by regurgitation of fPPG.

TL;DR: Analysis of inocula from Leishmania mexicana-infected Lutzomyia longipalpis sand flies revealed the size of the infectious dose, the underlying mechanism of parasite delivery by regurgitation, and the novel contribution made to infection by filamentous proteophosphoglycan (fPPG), a component of promastigote secretory gel found to accompany the parasites during transmission.
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The novel isoxazoline ectoparasiticide fluralaner: selective inhibition of arthropod γ-aminobutyric acid- and L-glutamate-gated chloride channels and insecticidal/acaricidal activity.

TL;DR: In agreement with the superior RDL on-target activity, fluralaner outperformed dieldrin and fipronil in insecticidal screens on cat fleas (Ctenocephalides felis), yellow fever mosquito larvae (Aedes aegypti) and sheep blowfly larvae (Lucilia cuprina), as well as in acar suicidal screens on cattle tick (R. microplus) adult females and Ornithodoros moubata nymphs.
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Proteophosphoglycans of Leishmania

TL;DR: The chemical structure, the ultrastructure, the genes and the potential functions of different members of this novel family of parasite glycoproteins are reviewed.
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Lipophosphoglycan is not required for infection of macrophages or mice by Leishmania mexicana

TL;DR: The results demonstrate that at least L.mexicana does not require LPG for experimental infections of macrophages or mice, and Leishmania mexicana LPG is therefore not a virulence factor in the mammalian host.
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Expression of lipophosphoglycan, high-molecular weight phosphoglycan and glycoprotein 63 in promastigotes and amastigotes of Leishmania mexicana.

TL;DR: Immunoblotting experiments demonstrate that amastigotes synthesize hydrophilic high-molecular weight compounds which stain blue with Stains-all and cross-react with the monoclonal and polyvalent antibodies suggesting the presence of similar phosphoglycan structures as in LPG.