Thomas J. Webster

TL;DR: The promise of nanomaterials for bone, cartilage, vascular, neural and bladder tissue engineering applications will be reviewed and as an important future area of research, the potential risk and toxicity ofnanomaterial synthesis and use related to human health are emphasized.

TL;DR: The present study suggests that nanophase metals should be further considered for orthopedic implant applications because osteoblast adhesion is a necessary prerequisite for subsequent functions (such as deposition of calcium-containing mineral) and material characterization studies revealed that nanometal surfaces possessed similar chemistry and only altered in degree of nanometer surface roughness when compared to their respective conventional counterparts.

TL;DR: Results of this study suggest that decreasing the particulate size into the nanometer regime and reducing crystallinity of calcium phosphate based materials may promote osteoblast adhesion to the same degree as the well-established techniques of functionalizing conventional HA with RGD.

TL;DR: The present in vitro study provided the first evidence that nano-structured surface features can significantly improve vascular cell densities; such design criteria can be used in the synthesis of the next-generation of more successful tissue-engineered vascular grafts.

TL;DR: It is suggested that nanophase ZnO and TiO(2) may reduce S. epidermidis adhesion and increase osteoblast functions necessary to promote the efficacy of orthopedic implants.