T
Thomas Jue
Researcher at University of California, Davis
Publications - 114
Citations - 4294
Thomas Jue is an academic researcher from University of California, Davis. The author has contributed to research in topics: Myoglobin & Skeletal muscle. The author has an hindex of 32, co-authored 110 publications receiving 4089 citations. Previous affiliations of Thomas Jue include University of California & Yale University.
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Journal ArticleDOI
Quantitation of Muscle Glycogen Synthesis in Normal Subjects and Subjects with Non-Insulin-Dependent Diabetes by 13C Nuclear Magnetic Resonance Spectroscopy
Gerald I. Shulman,Douglas L. Rothman,Thomas Jue,Peter J. Stein,Ralph A. DeFronzo,Robert G. Shulman +5 more
TL;DR: It is concluded that muscle glycogen synthesis is the principal pathway of glucose disposal in both normal and diabetic subjects and that defects in muscle glycogens synthesis have a dominant role in the insulin resistance that occurs in persons with NIDDM.
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Spatially localized 1H NMR spectra of metabolites in the human brain.
TL;DR: Using a surface coil, 1H NMR spectra from metabolites in the human brain are obtained by combining depth pulses with image-selected in vivo spectroscopy magnetic field gradient methods and while creatine relaxation times were the same in both, the N-acetylaspartate relaxation time was longer in white matter.
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Comparative analysis of NMR and NIRS measurements of intracellular PO2 in human skeletal muscle
Tuan Khanh Tran,Napapon Sailasuta,Ulrike Kreutzer,Ralph E. Hurd,Youngran Chung,Paul A. Molé,Shinya Kuno,Thomas Jue +7 more
TL;DR: The experimental results establish the feasibility and methodology to observe the deoxyMb and Hb signals in skeletal muscle, help clarify the origin of the NIRS signal, and set a stage for continuing study of O2regulation in skeletal Muscle.
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Myoglobin desaturation with exercise intensity in human gastrocnemius muscle
TL;DR: The O2 gradient from hemoglobin to the mitochondria can modulate the O2flux to meet the increased V˙o 2 in exercising muscle, but declining cellular levels during enhanced mitochondrial respiration suggests that O2 availability is not limiting during exercise.
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Myoglobin's old and new clothes: from molecular structure to function in living cells
TL;DR: The analysis suggests that important differences can be observed whether steady-state or transient conditions are considered, and the role of myoglobin in oxygen transport in vertebrate heart and skeletal muscle, in the diving seal during apnea and the possible role of the analogous leghemoglobin of plants is addressed.