T
Thomas Rowe
Researcher at Centers for Disease Control and Prevention
Publications - 59
Citations - 8447
Thomas Rowe is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Influenza A virus & Virus. The author has an hindex of 35, co-authored 58 publications receiving 7840 citations. Previous affiliations of Thomas Rowe include Southern Research Institute & United States Department of Agriculture.
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Journal ArticleDOI
Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness.
Kanta Subbarao,Alexander Klimov,Alexander Klimov,Alexander Klimov,Jacqueline M. Katz,Jacqueline M. Katz,Jacqueline M. Katz,Helen L. Regnery,Helen L. Regnery,Helen L. Regnery,Wilina Lim,Wilina Lim,Wilina Lim,Henrietta Hall,Henrietta Hall,Henrietta Hall,Michael L. Perdue,Michael L. Perdue,Michael L. Perdue,David E. Swayne,David E. Swayne,David E. Swayne,Catherine A. Bender,Catherine A. Bender,Catherine A. Bender,Jing Huang,Jing Huang,Jing Huang,Mark L. Hemphill,Mark L. Hemphill,Mark L. Hemphill,Thomas Rowe,Thomas Rowe,Thomas Rowe,Michael W. Shaw,Michael W. Shaw,Michael W. Shaw,Xiyan Xu,Xiyan Xu,Xiyan Xu,Keiji Fukuda,Keiji Fukuda,Keiji Fukuda,Nancy Cox,Nancy Cox,Nancy Cox +45 more
TL;DR: An avian H5N1 influenza A virus was isolated from a tracheal aspirate obtained from a 3-year-old child in Hong Kong with a fatal illness consistent with influenza, causing 87.5 to 100 percent mortality in experimentally inoculated White Plymouth Rock and White Leghorn chickens.
Journal ArticleDOI
Detection of Antibody to Avian Influenza A (H5N1) Virus in Human Serum by Using a Combination of Serologic Assays
Thomas Rowe,Robert A. Abernathy,Jean Hu-Primmer,William W. Thompson,Xiuhua Lu,Wilina Lim,Keiji Fukuda,Nancy J. Cox,Jacqueline M. Katz +8 more
TL;DR: A more sensitive microneutralization assay is developed to detect antibodies to avian influenza in humans and is being used for the seroepidemiologic investigations of the avian H5N1 influenza outbreak.
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Safety and Immunogenicity of an Inactivated Subvirion Influenza A (H5N1) Vaccine
TL;DR: A two-dose regimen of 90 mug of subvirion influenza A (H5N1) vaccine does not cause severe side effects and, in the majority of recipients, generates neutralizing antibody responses typically associated with protection against influenza.
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Comparisons of Highly Virulent H5N1 Influenza A Viruses Isolated from Humans and Chickens from Hong Kong
David L. Suarez,Michael L. Perdue,Nancy J. Cox,Thomas Rowe,Catherine A. Bender,Jing Huang,David E. Swayne +6 more
TL;DR: A small number of changes in hemagglutinin gene sequences defined two closely related subgroups, with both subgroups having human and chicken members, among the seven viruses examined from Hong Kong, and all seven viruses were highly pathogenic in chickens and caused similar lesions in experimental inoculations.
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Pathogenesis of avian influenza A (H5N1) viruses in ferrets.
TL;DR: It is demonstrated that both H5N1 viruses were highly virulent in the outbred ferret model, unlike the differential pathogenicity documented in inbred BALB/c mice.