T
Thomas S. Winokur
Researcher at University of Alabama at Birmingham
Publications - 60
Citations - 2076
Thomas S. Winokur is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Transforming growth factor & Myocyte. The author has an hindex of 25, co-authored 58 publications receiving 1980 citations. Previous affiliations of Thomas S. Winokur include National Institutes of Health & Fox Chase Cancer Center.
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Journal ArticleDOI
Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution
Lalage M. Wakefield,Thomas S. Winokur,R S Hollands,K Christopherson,A D Levinson,Michael B. Sporn +5 more
TL;DR: The results suggest that formation of latent complexes may switch endogenous TGF-beta 1 from an autocrine/paracrine mode of action to a more endocrine mode involving target organs distant from the site of synthesis.
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Repeat FDG-PET after neoadjuvant therapy is a predictor of pathologic response in patients with non-small cell lung cancer
Robert J. Cerfolio,Ayesha S. Bryant,Thomas S. Winokur,Buddhiwardhan Ohja,Alfred A. Bartolucci +4 more
TL;DR: The change in maxSUV on FDG-PET scan after neoadjuvant therapy holds a near linear relationship with pathologic response and is a more accurate predictor than the change of size on CT scan.
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Hepatic metastases: liposomal Gd-DTPA-enhanced MR imaging.
Evan C. Unger,Thomas S. Winokur,P MacDougall,J S Rosenblum,Michael Clair,Robert A. Gatenby,C Tilcock +6 more
TL;DR: The results suggest that paramagnetic liposomes may become a useful MR imaging contrast agent for magnetic resonance imaging of the liver in rats with hepatic metastases.
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Role of transforming growth factor-beta in maintenance of function of cultured neonatal cardiac myocytes. Autocrine action and reversal of damaging effects of interleukin-1.
TL;DR: It is reported that exogenous TGF-beta stabilizes the beating rate of neonatal rat cardiac myocytes cultured on fibroblast matrix, and sustains their spontaneous rhythmic beating in serum-free medium, and it is shown that endogenous T GF-beta secreted by these myocytes acts in an autocrine fashion to maintain their beating rate.
Journal ArticleDOI
Expression of transforming growth factor-beta s 1-4 in chicken embryo chondrocytes and myocytes.
Sonia B. Jakowlew,Pamela J. Dillard,Thomas S. Winokur,Kathleen C. Flanders,Michael B. Sporn,Anita B. Roberts +5 more
TL;DR: In this paper, the expression of TGF-beta s 2, 3, and 4 mRNAs was detected in cultured chondrocytes and myocytes, but not TGF beta 1 mRNA, in vitro and in vivo.