T
Thomas Sun
Researcher at National Administrative Department of Statistics
Publications - 4
Citations - 657
Thomas Sun is an academic researcher from National Administrative Department of Statistics. The author has contributed to research in topics: Immune receptor & ZAP70. The author has an hindex of 3, co-authored 4 publications receiving 619 citations.
Papers
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Journal ArticleDOI
R406, an Orally Available Spleen Tyrosine Kinase Inhibitor Blocks Fc Receptor Signaling and Reduces Immune Complex-Mediated Inflammation
Sylvia Braselmann,Vanessa Taylor,Haoran Zhao,Su Wang,Catherine Sylvain,Muhammad Baluom,Kunbin Qu,Ellen Herlaar,Angela Lau,Chi Young,Brian R Wong,Scott Lovell,Thomas Sun,Gary Park,Ankush Argade,Stipo Jurcevic,Polly Pine,Rajinder Singh,Elliott B. Grossbard,Donald G. Payan,Esteban Masuda +20 more
TL;DR: A first-inhuman study is reported showing that R406 is orally bioavailable, achieving exposures capable of inhibiting Syk-dependent IgE-mediated basophil activation and showing R406 potential for modulating Syk activity in human disease.
Patent
Prodrugs of 2,4-pyrimidinediamine compounds and their uses
TL;DR: In this article, the prodrugs of biologically active 2,4-pyrimidinediamine compounds, compositions comprising the pro drugs, intermediates and methods for synthesizing them, and methods of using them in a variety of applications are presented.
Patent
Substituted diphenyl heterocycles useful for treating HCV infection
TL;DR: In this paper, substituted diphenyl heterocycle compounds and pharmaceutical compositions thereof were used to inhibit replication of HCV virus and to treat or prevent HCV infections, and the use of the compounds and compositions to inhibit HCV replication and/or proliferation was discussed.
Patent
Prodrugs of 2,4-pyrimidinediamine compounds and of their uses.
TL;DR: A compound of structural formula is a pharmaceutically acceptable salt or hydrate, solvate or N-oxide of the compound or salt as mentioned in this paper, which is a generic term for any compound.