T
Thomas T.Y. Wang
Researcher at United States Department of Agriculture
Publications - 111
Citations - 4835
Thomas T.Y. Wang is an academic researcher from United States Department of Agriculture. The author has contributed to research in topics: LNCaP & Prostate cancer. The author has an hindex of 34, co-authored 101 publications receiving 4166 citations. Previous affiliations of Thomas T.Y. Wang include Agricultural Research Service & National Institutes of Health.
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Journal ArticleDOI
Molecular effects of genistein on estrogen receptor mediated pathways
TL;DR: Genistein, though estrogenic, can interfere with the effects of estradiol and prolonged exposure to genistein resulted in a decrease in estrogen receptor mRNA level as well as a decreased response to stimulation byEstradiol.
Journal Article
Effects of Estrogen on Apoptotic Pathways in Human Breast Cancer Cell Line MCF-7
Thomas T.Y. Wang,James M. Phang +1 more
TL;DR: Evidence is provided that responses of breast epithelial cells toward a steroid sex hormone involve regulation of the apoptotic pathway, and that pretreatment with 17 beta-estradiol protected MCF-7 cells from apoptosis.
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Effect of curcumin on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells.
TL;DR: Results suggest that the chemopreventive effect of curcumin may be due, in part, to its ability to compete with aryl hydrocarbons for both the AhR and CYP1A1.
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Encapsulation of indole-3-carbinol and 3,3′-diindolylmethane in zein/carboxymethyl chitosan nanoparticles with controlled release property and improved stability
TL;DR: Zein and zein/CMCS nanoparticles demonstrated similar protection for both I3C and DIM against ultraviolet (UV) light, attributed mainly to the contribution of the zein protein, and encapsulation efficiency was greatly improved.
Journal Article
Stimulation of pS2 Expression by Diet-derived Compounds
TL;DR: Results indicated that the phenolic compounds daidzein, equol, nordihydroguaiaretic acid, enterolactone, and kaempferol were able to elicit an estrogen-like response, while quercetin and enterodiol were not.