T
Thomas W. Flaig
Researcher at University of Colorado Boulder
Publications - 215
Citations - 17211
Thomas W. Flaig is an academic researcher from University of Colorado Boulder. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 40, co-authored 180 publications receiving 14477 citations. Previous affiliations of Thomas W. Flaig include American Society of Clinical Oncology & Charité.
Papers
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Journal ArticleDOI
A phase II study of olaparib (AZD2281) in patients (Pts) with metastatic/advanced urothelial carcinoma and other genitourinary (GU) tumors with DNA-repair defects.
Elias A. Chandran,Nicholas I. Simon,Scot A. Niglio,Lisa Ley,Lisa M. Cordes,Rouf Banday,Chimene Kesserwan,Kent W. Mouw,Andre Kydd,Salah Boudjadi,Ludmila Prokunina-Olsson,Mamta Parikh,Thomas W. Flaig,Rana R. McKay,Arash Rezazadeh,S. Percy Ivy,Giovanni Maria Iannantuono,Saad O Atiq,Seth M. Steinberg,Andrea B. Apolo +19 more
TL;DR: Olaparib is a poly-ADP-ribose polymerase (PARP) inhibitor that induces synthetic lethality in tumor cells with dysfunctional DNA damage repair (DDR) from loss of function of BRCA or other DDR genes as mentioned in this paper .
Journal ArticleDOI
National trends in clinical and pathologic staging for upper tract urothelial carcinoma: Implications for neoadjuvant chemotherapy.
Rodrigo Rodrigues Pessoa,Jeffrey C. Morrison,Badrinath R. Konety,Boris Gershman,Paul Maroni,Janet Baack Kukreja,Nicholas G. Cost,Thomas W. Flaig,Elizabeth R. Kessler,Pranav Sharma,Simon P. Kim,Simon P. Kim +11 more
TL;DR: In this paper, the rates of appropriate clinical use of perioperative chemotherapy for upper tract urothelial carcinoma (UTUC) and identify clinicopathologic factors associated with aggressive UTUC amongst patients undergoing radical nephroureterectomy (RNU) for clinically localized disease.
Journal Article
Sequencing medical therapy in prostate cancer: not as easy as 1-2-3.
TL;DR: With the emergence of several new agents for the treatment of advanced prostate cancer, new questions have arisen regarding the optimal sequence or combination of these agents.
Journal ArticleDOI
Patterns of Treatment and Outcomes in Older Men With Penile Cancer: A SEER Dataset Analysis
Maria T Bourlon,Haydee Cristina Verduzco-Aguirre,Elizabeth Molina,E. Meyer,Elizabeth E. Kessler,Simon P. Kim,Philippe E. Spiess,Thomas W. Flaig +7 more
TL;DR: Older patients are less likely to receive surgery, chemotherapy and radiotherapy for penile cancer, and stage at diagnosis, and receipt of primary site surgery were associated with a higher incidence ofPenile cancer death, on multivariate analysis.