T
Timothy J. Kamp
Researcher at University of Wisconsin-Madison
Publications - 195
Citations - 15932
Timothy J. Kamp is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 53, co-authored 173 publications receiving 13913 citations. Previous affiliations of Timothy J. Kamp include University of Illinois at Chicago & University of Wisconsin Hospital and Clinics.
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Journal ArticleDOI
Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling
Xiaojun Lian,Cheston Hsiao,Gisela F. Wilson,Kexian Zhu,Laurie B. Hazeltine,Samira M. Azarin,Kunil K. Raval,Kunil K. Raval,Jianhua Zhang,Jianhua Zhang,Timothy J. Kamp,Timothy J. Kamp,Sean P. Palecek +12 more
TL;DR: It is shown that temporal modulation of Wnt signaling is both essential and sufficient for efficient cardiac induction in hPSCs under defined, growth factor-free conditions.
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Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions
Xiaojun Lian,Jianhua Zhang,Samira M. Azarin,Kexian Zhu,Laurie B. Hazeltine,Xiaoping Bao,Cheston Hsiao,Timothy J. Kamp,Sean P. Palecek +8 more
TL;DR: Functional human cardiomyocytes differentiated via these protocols may constitute a potential cell source for heart disease modeling, drug screening and cell-based therapeutic applications.
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Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
Jianhua Zhang,Gisela F. Wilson,Andrew G. Soerens,Chad H. Koonce,Junying Yu,Sean P. Palecek,James A. Thomson,Timothy J. Kamp +7 more
TL;DR: It is concluded that human iPS cells are a viable option as an autologous cell source for cardiac repair and a powerful tool for cardiovascular research.
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Human Embryonic Stem Cells Develop Into Multiple Types of Cardiac Myocytes. Action Potential Characterization
TL;DR: In this article, the authors characterized the contractions and action potentials (APs) from beating EB outgrowths cultured for 40 to 95 days and measured spontaneous and electrical field-stimulated contractions with video edge detection microscopy.
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High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents
Junyi Ma,Liang Guo,Steve Fiene,Blake D. Anson,James A. Thomson,Timothy J. Kamp,Kyle L. Kolaja,Bradley J. Swanson,Craig T. January +8 more
TL;DR: Detailed electrophysiological characterization of highly pure hiPSC-derived cardiomyocytes concludes that they have ionic currents and channel gating properties underlying their APs and EADs that are quantitatively similar to those reported for human cardiac myocytes.