T
Timothy Plant
Researcher at University of Birmingham
Publications - 10
Citations - 267
Timothy Plant is an academic researcher from University of Birmingham. The author has contributed to research in topics: Renal function & Monoclonal antibody. The author has an hindex of 6, co-authored 10 publications receiving 216 citations.
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Journal ArticleDOI
Non-cirrhotic Intrahepatic Portal Hypertension: Associated Gut Diseases and Prognostic Factors
Chundamannil E. Eapen,Peter Nightingale,Stefan G. Hubscher,Peter J. L. Lane,Timothy Plant,Dimitris Velissaris,Elwyn Elias +6 more
TL;DR: The data supports a role for intestinal disease in the pathogenesis of intrahepatic portal vein occlusion leading to NCIPH and identifies prognostic factors that report progression to liver failure in 53% of NCIPh patients followed-up at a tertiary referral center.
Journal ArticleDOI
IgG from myeloperoxidase–antineutrophil cytoplasmic antibody–positive patients stimulates greater activation of primed neutrophils than IgG from proteinase 3–antineutrophil cytoplasmic antibody–positive patients
TL;DR: Differences in activation of PMN by these antibodies may determine some differences between WG and MPA, and in vitro MPO-ANCA-positive IgG preparations are more activating than PR3-AN CA-positive igG preparations.
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Development of a highly-sensitive multi-plex assay using monoclonal antibodies for the simultaneous measurement of kappa and lambda immunoglobulin free light chains in serum and urine.
John Campbell,Mark Cobbold,Yanyun Wang,Margaret Goodall,Sarah Bonney,Anita Chamba,Jane Birtwistle,Timothy Plant,Zaheer Afzal,Roy Jefferis,Mark T. Drayson +10 more
TL;DR: An improved method using specific mouse anti-human FLC monoclonal antibodies (mAbs) is described, showing that the mAbs are at least close to the ideal of detecting FLC from all patients and neoplastic plasma cell clones.
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Establishing the prevalence of common tissue-specific autoantibodies following severe acute respiratory syndrome coronavirus 2 infection.
Alex G. Richter,Adrian M Shields,Abid Karim,David Birch,Sian E Faustini,Lora Steadman,Kerensa Ward,Timothy Plant,Gary M. Reynolds,Tonny Veenith,Adam F. Cunningham,Mark T. Drayson,David C. Wraith +12 more
TL;DR: In this article, the prevalence of autoantibodies associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was investigated in 84 individuals who were previously infected with SARS CoV 2, suffering from COVID-19 of varying severity.
Journal ArticleDOI
Humoral immunity in late-onset Pre-eclampsia and linkage with angiogenic and inflammatory markers.
Nadia Sarween,Nadia Sarween,Mark T. Drayson,James Hodson,Ellen Knox,Timothy Plant,Clara Day,Graham Lipkin +7 more
TL;DR: This work compared markers of humoral immunity in PE and their relationship to circulating markers of inflammation, angiogenic factors, and renal function to determine the implication of immune mechanisms.