世界経済・社会統計 = World development indicators

Summary Background Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well described. Methods In this retrospective, multicentre cohort study, we included all adult inpatients (≥18 years old) with laboratory-confirmed COVID-19 from Jinyintan Hospital and Wuhan Pulmonary Hospital (Wuhan, China) who had been discharged or had died by Jan 31, 2020. Demographic, clinical, treatment, and laboratory data, including serial samples for viral RNA detection, were extracted from electronic medical records and compared between survivors and non-survivors. We used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death. Findings 191 patients (135 from Jinyintan Hospital and 56 from Wuhan Pulmonary Hospital) were included in this study, of whom 137 were discharged and 54 died in hospital. 91 (48%) patients had a comorbidity, with hypertension being the most common (58 [30%] patients), followed by diabetes (36 [19%] patients) and coronary heart disease (15 [8%] patients). Multivariable regression showed increasing odds of in-hospital death associated with older age (odds ratio 1·10, 95% CI 1·03–1·17, per year increase; p=0·0043), higher Sequential Organ Failure Assessment (SOFA) score (5·65, 2·61–12·23; p Interpretation The potential risk factors of older age, high SOFA score, and d-dimer greater than 1 μg/mL could help clinicians to identify patients with poor prognosis at an early stage. Prolonged viral shedding provides the rationale for a strategy of isolation of infected patients and optimal antiviral interventions in the future. Funding Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences; National Science Grant for Distinguished Young Scholars; National Key Research and Development Program of China; The Beijing Science and Technology Project; and Major Projects of National Science and Technology on New Drug Creation and Development.

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

This chapter discusses leading problems linked to energy that the world is now confronting and to propose some ideas concerning possible solutions. Oil deserves special attention among all energy sources. Since the beginning of 1981, it has merely been continuing and enhancing the downward movement in consumption and prices caused by excessive rises, especially for light crudes such as those from Africa, and the slowing down of worldwide economic growth. Densely-populated oil-producing countries need to produce to live, to pay for their food and their equipment. If the economic growth of the industrialized countries were to be 4%, even if investment in the rational use of energy were pushed to the limit and the development of nonpetroleum energy sources were also pursued actively, it would be extremely difficult to prevent a sharp rise in prices. It is evident that it is absolutely necessary to pursue actively the development of coal, natural gas, and nuclear power if a physical shortage of energy is not to block economic growth.

World energy outlook

The erythrocytes of mammals represent a good model to evaluate the cytotoxicity of molecules, organic and inorganic, natural or synthetic, by cellular damage measure. Indeed, before any investigation on the mechanism of action of different molecules, it is important to perform a cytotoxicity assay. Among the different cytotoxicity assays that assess a possible toxicity in the red blood cells is the rate of haemolysis. This essay is based on the evaluation of the alterations of red cell membranes in the presence of an eventual xenobiotic. Red blood cells are the main cells in circulation, and they are responsible for transporting oxygen; in fact, any alterations of this process could be lethal. The plasma membrane of red blood cells is a multi-component structure such as to confer to these cells their characteristic biconcave shape, high flexibility, elasticity and deformability. However, there are clear signs of cellular suffering if there are any alterations to this structure. One method of toxicity assessment is based on measurement of the efflux of haemoglobin from suspended red blood cells. Haemolysis, and therefore the loss of haemoglobin, is the signal stability of the cell membrane of the erythrocytes. In recent years, the discovery of programmed cell death in mammalian red blood cells presented a diversification of the response to injury by these a-nucleated cells. This review shows that mammals' erythrocytes might serve well as a model cell to study on the cellular and molecular mechanisms of many treatments.

The use of erythrocyte fragility to assess xenobiotic cytotoxicity

Energy and exergy analysis and optimization of Kalina cycle coupled with a coal fired steam power plant

In this article, we analyse the factors that determine the fatality rates across 29 economies spread across both the developing and developed world. Recent emerging literature and expert op...

https://journals.sagepub.com/doi/pdf/10.1177/0972150920929897

Why Do COVID-19 Fatality Rates Differ Across Countries? An Explorative Cross-country Study Based on Select Indicators

PurposeThe study aims to map the links between Industry 4.0 (I-4.0) technologies and circular economy (CE) for sustainable operations and their role to achieving the selected number of sustainable development goals (SDGs).Design/methodology/approachThe study adopts a systematic literature review method to identify 76 primary studies that were published between January 2010 and December 2020. The authors synthesized the existing literature using Scopus database to investigate I-4.0 technologies and CE to select SDGs.FindingsThe findings of the study bridge the gap in the literature at the intersection between I-4.0 and sustainable operations in line with the regenerate, share, optimize, loop, virtualize and exchange (ReSOLVE) framework leading to CE practices. Further, the study also depicts the CE practices leading to the select SDGs (“SDG 6: Clean Water and Sanitation,” “SDG 7: Affordable and Clean Energy,” “SDG 9: Industry, Innovation and Infrastructure,” “SDG 12: Responsible Consumption and Production” and “SDG 13: Climate Action”). The study proposes a conceptual framework based on the linkages above, which can help organizations to realign their management practices, thereby achieving specific SDGs.Originality/valueThe originality of the study is substantiated by a unique I-4.0-sustainable operations-CE-SDGs (ISOCES) framework that integrates I-4.0 and CE for sustainable development. The framework is unique, as it is based on an in-depth and systematic review of the literature that maps the links between I-4.0, CE and sustainability.

/pdf/mapping-the-links-between-industry-4-0-circular-economy-and-131v6ce5.pdf

Mapping the links between Industry 4.0, circular economy and sustainability: a systematic literature review

The study examines the corporate social responsibility (CSR) strategies and activities of firms as disclosed in annual reports, and explores its linkages to accounting and market performance of firms. The study examines the annual reports of a sample of 30 firms (out of 50) belonging to the benchmark index of the National Stock Exchange of India and tracks these reports for evidence of CSR activities over a 5-year period from 2007 to 2011. The study employs content analysis to study CSR disclosure and classifies and rates these activities using items from an established scale followed by construction of category-wise CSR indexes. The association of these indexes with firm performance is explored through a pooled regression model after provisioning for control variables and lag effects. The study finds that CSR reporting may not have any significant impact on accounting and market performance of the firm in the short term but environment-oriented CSR disclosure may be negatively related to the market perfo...

Corporate Social Responsibility Reporting in India: Exploring Linkages with Firm Performance:

The study examines the impact of the power sector reforms on the electricity generation industry at the state level in India through a case study of the state of Gujarat. The state has been selected as a unit of study to bring out the regional variances that are not captured at a more aggregate or country level study. The study finds that the reforms have led to the emergence of various ownership structures with associated changes in fuel mix and technology. There has been a steady improvement in the efficiency of generation with reduction in carbon intensities. The carbon intensities so obtained are then used for construction of a baseline for the state, which is then projected up to the year 2010. The study reports a considerable decline in the baseline, which is expected to touch 0.18 Kg per kWh in 2010.. With the projected growth in the share of imported coal and natural gas, the dominance of domestic coal based generation is projected to decline and the state is expected to proceed along a path of declining carbon intensities. .

Impact of Power Sector Reforms on Technology, Efficiency and Emissions: Case Study of Gujarat, India

Clientelism may lead to the underprovision of services which are deemed suitable for decentralisation. Water distribution and drainage services, managed from a lower level of municipal authority, are liable to be affected by clientelism and consequent underprovision. Water quality, maintained from a higher municipal layer, is not likely to be affected by clientelism. Capture by politically influential and dominant social and religious groups is likely to take place for important services like water supply. The article suggests that awareness, measurability, importance and resource intensiveness of service are additional factors to be considered for assessing the suitability of a sector for decentralisation.

Tirthankar Nag

Papers

Why Do COVID-19 Fatality Rates Differ Across Countries? An Explorative Cross-country Study Based on Select Indicators

Mapping the links between Industry 4.0, circular economy and sustainability: a systematic literature review

Corporate Social Responsibility Reporting in India: Exploring Linkages with Firm Performance:

Impact of Power Sector Reforms on Technology, Efficiency and Emissions: Case Study of Gujarat, India

Dangers of Decentralisation in Urban Slums: A Comparative Study of Water Supply and Drainage Service Delivery in Kolkata, India