Showing papers by "Todd E. DeFor published in 2008"
TL;DR: The results do not support the selection of UCB units based on KIR-L status and suggest that Kir-L mismatching should be avoided in reduced intensity UCB transplantation.
143 citations
TL;DR: The HCT-CI, although a useful tool for capturing pretransplant comorbidity and risk-assessment, needs to be further validated prior to adopting it for routine clinical use.
65 citations
TL;DR: Serum ferritin is a good screening test but does not reliably predict tissue iron overload, and estimation of LIC should be considered before initiating therapy.
63 citations
TL;DR: This single center study studied the relative impact of donor source on outcomes following myeloablative hematopoietic stem cell transplantation for adult patients with acute lymphocytic leukemia (ALL) and found graft-versus-host disease (GVHD) was associated with improved LFS.
61 citations
TL;DR: The benefits of palifermin appear primarily to be limited to ameliorating mucotoxicity when given to allogeneic HCT recipients.
54 citations
TL;DR: It is concluded that similar transplant outcomes are achieved after allogeneic hematopoietic stem cell transplantation using MA conditioning in younger patients and NMA conditioning in older patients or those with prior autologous transplantation not eligible for MA conditioning.
52 citations
TL;DR: The data support the use of allogeneic HCT in the treatment of children with poor prognosis isolated CNS relapse, and risk factors for poor survival were: T cell leukemia or BCR-ABL gene rearrangement, history of marrow relapse,and receipt of HLA-mismatched marrow.
25 citations
TL;DR: A large number of patients with recurrent esophageal cancer are diagnosed with atypical central giant cell granuloma, but the prognostic and therapeutic implications of this condition are still poorly understood.
Abstract: 4528 Background: Accurate nodal staging has important prognostic and therapeutic implications for esophageal cancer patients yet there is a lack of information in the literature to guide clinicians...
3 citations
TL;DR: A revised HCT-CI based on a pure multiplicative model that assigns weights to comorbidities more efficiently and increases the discriminating and predictive power of the original H CT-CI for NRM and OS is proposed.
1 citations
1 citations