T
Tomohiro Murata
Researcher at Mie University
Publications - 50
Citations - 471
Tomohiro Murata is an academic researcher from Mie University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 39 publications receiving 378 citations.
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Journal ArticleDOI
Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension.
Mai Wakabayashi,Takayasu Mori,Kiyoshi Isobe,Eisei Sohara,Koichiro Susa,Yuya Araki,Motoko Chiga,Eriko Kikuchi,Naohiro Nomura,Yutaro Mori,Hiroshi Matsuo,Tomohiro Murata,Shinsuke Nomura,Takako Asano,Hiroyuki Kawaguchi,Shigeaki Nonoyama,Tatemitsu Rai,Sei Sasaki,Shinichi Uchida +18 more
TL;DR: WNK4 is a target for KLHL3-mediated Ubiquitination, and the impaired ubiquitination of WNK 4 is a common mechanism of human hereditary hypertension.
Journal ArticleDOI
Irradiation Prolongs Survival of Alport Mice
Kan Katayama,Mitsuo Kawano,Ichiro Naito,Hitoshi Ishikawa,Yoshikazu Sado,Nagisa Asakawa,Tomohiro Murata,Kazuki Oosugi,Michiyo Kiyohara,Eiji Ishikawa,Masaaki Ito,Shinsuke Nomura +11 more
TL;DR: The improved survival observed in Alport mice that received a transplant of wild-type bone marrow might be primarily attributed to as-yet-unidentified effects of irradiation.
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Role of haemodialytic therapy on left ventricular mechanical dyssynchrony in patients with end-stage renal disease quantified by speckle-tracking strain imaging
Tomohiro Murata,Kaoru Dohi,Katsuya Onishi,Emiyo Sugiura,Naoki Fujimoto,Kazuhide Ichikawa,Eiji Ishikawa,Mashio Nakamura,Shinsuke Nomura,Hideyuki Takeuchi,Tsutomu Nobori,Masaaki Ito +11 more
TL;DR: The presence of ESRD was associated with longitudinal and radial LV dyssynchronies and the impact of haemodialytic (HD) therapy on these parameters was elucidated by speckle-tracking strain imaging.
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Echocardiographic Assessment of Cardiac Structural and Functional Abnormalities in Patients With End-Stage Renal Disease Receiving Chronic Hemodialysis
Hiroshi Matsuo,Kaoru Dohi,Hirofumi Machida,Hideyuki Takeuchi,Toshikazu Aoki,Hiroyuki Nishimura,Masashi Yasutomi,Michiharu Senga,Takehiko Ichikawa,Kentaro Kakuta,Yasuhide Mizutani,Akiko Tanoue,Naoki Isaka,Kazuki Oosugi,Sukenari Koyabu,Masato Sakurai,Yoshihisa Fukui,Hitoshi Kakimoto,Tadafumi Sugimoto,Takahiro Ohnishi,Tomohiro Murata,Eiji Ishikawa,Ryuji Okamoto,Tomomi Yamada,Toru Ogura,Yuki Nishimura,Takashi Tanigawa,Shinsuke Nomura,Masakatsu Nishikawa,Masaaki Ito +29 more
TL;DR: Patients with ESRD on chronic HD have a high prevalence of cardiac structural and functional abnormalities including calcified aortic sclerosis and high age and intact parathyroid hormone (PTH) level were independently associated with low AVA index.
Journal ArticleDOI
COL4A6 is dispensable for autosomal recessive Alport syndrome
Tomohiro Murata,Kan Katayama,Kan Katayama,Toshitaka Oohashi,Timo Jahnukainen,Tomoko Yonezawa,Yoshikazu Sado,Eiji Ishikawa,Shinsuke Nomura,Karl Tryggvason,Masaaki Ito +10 more
TL;DR: Findings indicate that although α5 and α6 (IV) chains are induced in the glomerular basement membrane in autosomal recessive Alport syndrome, their induction does not seem to play a major compensatory role.