T
Tomoya Kitayama
Researcher at Kanazawa University
Publications - 11
Citations - 380
Tomoya Kitayama is an academic researcher from Kanazawa University. The author has contributed to research in topics: Neural stem cell & Neurosphere. The author has an hindex of 10, co-authored 11 publications receiving 376 citations.
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Regulation of neuronal differentiation by N-methyl-D-aspartate receptors expressed in neural progenitor cells isolated from adult mouse hippocampus
TL;DR: The results suggest that functional heteromeric NMDA receptors may be expressed constitutively in neural progenitor cells before differentiation to play a crucial role in commitment and differentiation to neurons in adult murine hippocampus.
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Possible regulation by N-methyl-d-aspartate receptors of proliferative progenitor cells expressed in adult mouse hippocampal dentate gyrus.
TL;DR: The results suggest that NMDA receptors may play a role crucial for maintenance of the integrity and function of proliferative neural progenitor cells through expression of the nuclear transcription factor activator protein‐1 in granule cells of the dentate gyrus in adult mouse brain.
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Consolidation of transient ionotropic glutamate signals through nuclear transcription factors in the brain.
TL;DR: Extracellular Glu signals may be differentially transduced into the nucleus to express AP1 with different assemblies between Jun and Fos family members, and thereby to modulate de novo synthesis of the individual target proteins at the level of gene transcription in the hippocampus.
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Activation of GABAA receptors facilitates astroglial differentiation induced by ciliary neurotrophic factor in neural progenitors isolated from fetal rat brain
Masanori Yoneyama,Masaki Fukui,Noritaka Nakamichi,Tomoya Kitayama,Hideo Taniura,Yukio Yoneda +5 more
TL;DR: Results suggest that prior activation of GABAAR may preferentially facilitate the commitment by CNTF of neural progenitor cells toward an astroglial lineage after simulation of the self‐replication activity in the developing rat brain.
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Group III metabotropic glutamate receptor activation suppresses self‐replication of undifferentiated neocortical progenitor cells
Noritaka Nakamichi,Kohei Yoshida,Yukichi Ishioka,Juliet O. Makanga,Masaki Fukui,Masanori Yoneyama,Tomoya Kitayama,Nobuhiro Nakamura,Hideo Taniura,Yukio Yoneda +9 more
TL;DR: The results suggest that group III mGluR may be functionally expressed to suppress self‐renewal capacity through a mechanism related to cAMP formation with promotion of subsequent differentiation into astroglial lineage in neural progenitors.