Toshio Heike

TL;DR: It is strongly suggested that STAT3 activation is required and sufficient to maintain the undifferentiated state of ES cells.

TL;DR: It is proposed that pX or E2 protein, both in T cells and fibroblasts, activates cellular component(s) in the signal transduction pathway which results in the activation of lymphokine genes in the absence of extracellular stimuli.

TL;DR: Investigation of the effects of dexamethasone, cyclosporin A, FK506, and pyrrolidine dithiocarbamate on the induction of the ICAM-1 gene by cytokines in fibroblasts suggests that PDTC inhibits ICAM -1 gene expression by inhibiting the association of NF-kappa B (or NF-Kappa B-like) protein with the ICam-1 kappa B site.

TL;DR: B104 cell death was shown to be quite distinct from that of WEHI-231 in cell death kinetics, the mode of cell death, and the response to cyclosporin A, indicating that the death of B104 cells resulting from surface IgM cross-linking represents a hitherto undefined mode of programmed cell death.

TL;DR: Results suggest that brain-derived neurotrophic factor, its receptor trkB, and NT-3 are involved in the reorganization of the somatosensory and visual signals in the anterior bank of the intraparietal sulcus when monkeys are learning the use of the tool.