T
Toshio Suzuki
Researcher at Akita University
Publications - 129
Citations - 3379
Toshio Suzuki is an academic researcher from Akita University. The author has contributed to research in topics: Transplantation & Pharmacokinetics. The author has an hindex of 34, co-authored 123 publications receiving 3244 citations. Previous affiliations of Toshio Suzuki include Sony Broadcast & Professional Research Laboratories.
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Journal ArticleDOI
Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients.
Norihiko Tsuchiya,Shigeru Satoh,Hitoshi Tada,Zhenhua Li,Chikara Ohyama,Kazunari Sato,Toshio Suzuki,Tomonori Habuchi,Tetsuro Kato +8 more
TL;DR: Kidney transplant recipients with the CYP3A5 *1 allele required a higher daily tacrolimus dose compared with those with the cytochrome P450 3A5*3/*3 genotype to maintain both the target trough level and AUC0–12, suggesting that this polymorphism is useful for determining the appropriate dose of tacolimus.
Journal ArticleDOI
Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluvoxamine in Japanese depressed patients
Keizo Yoshida,Kenichi Ito,Kazuhiro Sato,Hitoshi Takahashi,Mitsuhiro Kamata,Hisashi Higuchi,Tetsuo Shimizu,Kunihiko Itoh,Kazuyuki Inoue,Takehiko Tezuka,Toshio Suzuki,Tadashi Ohkubo,Kazunobu Sugawara,Koichi Otani +13 more
TL;DR: The present study suggests that fluvoxamine is not less effective in depressive patients carrying the s allele than in the ones carrying the l allele and it is not more effective in Japanese than in Caucasians.
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Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients
Masatomo Miura,Shigeru Satoh,Kazuyuki Inoue,Hideaki Kagaya,Mitsuru Saito,Takamitsu Inoue,Toshio Suzuki,Tomonori Habuchi +7 more
TL;DR: The dose-adjusted area under the cuve (AUC)6–12 of MPA, an estimate of enterohepatic recirculation, was greater in SLCO1B3 T334G GG (or G699A AA) carriers than in TT carriers (orG699A GG) (40 vs. 25 ng·h/mL per milligram, respectively, P = 0.0497).
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Prediction of Antidepressant Response to Milnacipran by Norepinephrine Transporter Gene Polymorphisms
Keizo Yoshida,Hitoshi Takahashi,Hisashi Higuchi,Mitsuhiro Kamata,Kenichi Ito,Kazuhiro Sato,Shingo Naito,Tetsuo Shimizu,Kunihiko Itoh,Kazuyuki Inoue,Toshio Suzuki,Charles B. Nemeroff +11 more
TL;DR: The presence of the T allele of the NET T-182C polymorphism was associated with a superior antidepressant response, whereas the A/A genotype of theNET G1287A polymorphismwas asso...
Journal ArticleDOI
Monoamine oxidase: A gene polymorphism, tryptophan hydroxylase gene polymorphism and antidepressant response to fluvoxamine in Japanese patients with major depressive disorder
Keizo Yoshida,Shingo Naito,Hitoshi Takahashi,Kazuhiro Sato,Kenichi Ito,Mitsuhiro Kamata,Hisashi Higuchi,Tetsuo Shimizu,Kunihiko Itoh,Kazuyuki Inoue,Takehiko Tezuka,Toshio Suzuki,Tadashi Ohkubo,Kazunobu Sugawara,Koichi Otani +14 more
TL;DR: The present study fails to demonstrate that the genetic polymorphisms of MAOA-VNTR and TPH-A218C affect the antidepressant effect of fluvoxamine in Japanese patients with major depressive disorder.