T
Toshiya Ochiai
Researcher at Kyoto Prefectural University of Medicine
Publications - 149
Citations - 2681
Toshiya Ochiai is an academic researcher from Kyoto Prefectural University of Medicine. The author has contributed to research in topics: Cancer & Hepatectomy. The author has an hindex of 26, co-authored 148 publications receiving 2405 citations.
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Journal ArticleDOI
Novel diagnostic value of circulating miR-18a in plasma of patients with pancreatic cancer.
R Morimura,Shuhei Komatsu,Daisuke Ichikawa,Hideyuki Takeshita,Masahiro Tsujiura,H Nagata,Hirotaka Konishi,Afonso A Shiozaki,Hisashi Ikoma,Kazuma Okamoto,Toshiya Ochiai,Hiroki Taniguchi,Eigo Otsuji +12 more
TL;DR: Circulating miR-18a might provide new complementary tumour markers for pancreatic cancer as well as stably detectable in the plasma/serum.
Journal ArticleDOI
Clinical impact of circulating miR-221 in plasma of patients with pancreatic cancer.
Tsutomu Kawaguchi,Shuhei Komatsu,Daisuke Ichikawa,R Morimura,Masahiro Tsujiura,Hirotaka Konishi,Hideyuki Takeshita,H Nagata,Tomohiro Arita,Shoji Hirajima,Atushi Shiozaki,Hisashi Ikoma,Kazuma Okamoto,Toshiya Ochiai,Hiroki Taniguchi,Eigo Otsuji +15 more
TL;DR: Plasma miR-221 could be a useful biomarker for cancer detection, monitoring tumour dynamics and predicting malignant outcomes inPCa patients, and may contribute to clinical decision making in PCa treatments.
Journal ArticleDOI
Optimal duration of the early and late recurrence of hepatocellular carcinoma after hepatectomy.
Yusuke Yamamoto,Hisashi Ikoma,Ryo Morimura,Hirotaka Konishi,Yasutoshi Murayama,Shuhei Komatsu,Atsushi Shiozaki,Yoshiaki Kuriu,Takeshi Kubota,Masayoshi Nakanishi,Daisuke Ichikawa,Hitoshi Fujiwara,Kazuma Okamoto,Chouhei Sakakura,Toshiya Ochiai,Eigo Otsuji +15 more
TL;DR: Seventeen months after hepatectomy is a useful cut-off value between early and late recurrence of HCC based on the prognosis and different etiologies.
Journal ArticleDOI
Plasma microRNA profiles: identification of miR-744 as a novel diagnostic and prognostic biomarker in pancreatic cancer
Mahito Miyamae,Shuhei Komatsu,Daisuke Ichikawa,Tsutomu Kawaguchi,Shoji Hirajima,Wataru Okajima,Takuma Ohashi,Taisuke Imamura,Hirotaka Konishi,Atsushi Shiozaki,Ryo Morimura,Hisashi Ikoma,Toshiya Ochiai,Kazuma Okamoto,Hiroki Taniguchi,Eigo Otsuji +15 more
TL;DR: A high level of plasma miR-744 contributed to poorer progression-free survival of non-operable PCa patients who underwent gemcitabine-based chemotherapy and might be useful biomarker for screening PCa, monitoring, and predicting poor prognosis and chemoresistance in PCa Patients.
Journal ArticleDOI
HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells.
Atsushi Matsumura,Takeshi Kubota,Hiroaki Taiyoh,Hitoshi Fujiwara,Kazuma Okamoto,Daisuke Ichikawa,Atsushi Shiozaki,Shuhei Komatsu,Masayoshi Nakanishi,Yoshiaki Kuriu,Yasutoshi Murayama,Hisashi Ikoma,Toshiya Ochiai,Yukihito Kokuba,Takahiro Nakamura,Kunio Matsumoto,Eigo Otsuji +16 more
TL;DR: The results demonstrate that VEGF expression was reduced in homografts of CT26-NK4 cells, compared to those of the control cells, and suggest that HGF/c‑Met signalling may be a promising target for anti-angiogenic strategies.