T
Toshiyuki Yamamoto
Researcher at Fukushima Medical University
Publications - 681
Citations - 8596
Toshiyuki Yamamoto is an academic researcher from Fukushima Medical University. The author has contributed to research in topics: Medicine & Psoriasis. The author has an hindex of 42, co-authored 598 publications receiving 7643 citations. Previous affiliations of Toshiyuki Yamamoto include University of Cologne & Tokyo Medical and Dental University.
Papers
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Journal ArticleDOI
Sustained Activation of Fibroblast Transforming Growth Factor-β/Smad Signaling in a Murine Model of Scleroderma
Shinsuke Takagawa,Gabriella Lakos,Yasuji Mori,Toshiyuki Yamamoto,Kiyoshi Nishioka,John Varga +5 more
TL;DR: Results indicate that bleomycin-induced murine scleroderma is associated with rapid and sustained induction of transforming growth factor-beta/Smad signaling in resident dermal fibroblasts, raising the possibility that Smads plays an important part in the pathogenesis of fibrosis, and may therefore represent targets for selective anti-fibrotic interventions.
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Bleomycin and the skin.
TL;DR: The use of bleomycin for various skin disorders, as well as the risk factors and cutaneous side-effects resulting from its use are discussed.
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Anti-sclerotic Effect of Transforming Growth Factor-β Antibody in a Mouse Model of Bleomycin-Induced Scleroderma
TL;DR: The results suggest that administration of an antibody against TGF-beta is useful in preventing experimental dermal sclerosis induced by bleomycin and raises a possibility of the therapeutic approach of anti-TGF- beta antibody in scleroderma.
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Plasticity of central motor and sensory pathways in a case of unilateral extensive cortical dysplasia: Investigation of magnetic resonance imaging, transcranial magnetic stimulation, and short-latency somatosensory evoked potentials
TL;DR: It is concluded that reorganization of primary motor and sensory cortex occurs when there is unilateral extensive brain damage in early gestation.
Journal Article
Nitric oxide production and inducible nitric oxide synthase expression in systemic sclerosis.
TL;DR: The results suggest that increased NO levels may contribute to the abnormal regulation of fibroblasts in the fibrotic process in SSc.