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Ursula Theocharidis
Researcher at Ruhr University Bochum
Publications - 10
Citations - 341
Ursula Theocharidis is an academic researcher from Ruhr University Bochum. The author has contributed to research in topics: Neural stem cell & Stem cell. The author has an hindex of 6, co-authored 10 publications receiving 284 citations.
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Journal ArticleDOI
Chondroitin sulfates are required for fibroblast growth factor-2-dependent proliferation and maintenance in neural stem cells and for epidermal growth factor-dependent migration of their progeny.
Swetlana Sirko,Alexander von Holst,Anika Weber,Andrea Wizenmann,Ursula Theocharidis,Magdalena Götz,Andreas Faissner +6 more
TL;DR: It is concluded that neural stem/progenitor cell subpopulations reside in neurospheres that are distinguishable by their responsiveness to FGF‐2 and EGF which is differentially regulated by CS‐carbohydrate structures.
Journal ArticleDOI
The extracellular matrix niche microenvironment of neural and cancer stem cells in the brain.
TL;DR: The present review focuses on glioblastoma multiforme (GBM) and points out that extracellular matrix (ECM) molecules and their complementary receptors influence the behavior of NSCs/CSCs as well as brain tumor progression.
Journal ArticleDOI
Tenascin-C in the matrisome of neural stem and progenitor cells.
TL;DR: The current state of research suggesting that tenascin‐C plays an important modulatory role with regard to neural stem and glial progenitor cell proliferation and differentiation is discussed and tenascIn‐C and/or ‐derived peptides may be promising tools for the construction of synthetic stem cell environments.
Book ChapterDOI
Regulation of the neural stem cell compartment by extracellular matrix constituents.
TL;DR: Increasing evidence is summarized that the extracellular matrix (ECM) of the stem cell environment is of crucial importance for the biology of this cellular compartment.
Journal ArticleDOI
Analysis of combinatorial variability reveals selective accumulation of the fibronectin type III domains B and D of tenascin-C in injured brain.
Alexandre Dobbertin,Stefan Czvitkovich,Ursula Theocharidis,Jeremy Garwood,Melissa R. Andrews,Francesca Properzi,Rachel Lin,James W. Fawcett,Andreas Faissner +8 more
TL;DR: Estimation of the expression pattern of Tnc variants after cortical lesions and after treatment of astrocytes with various cytokines suggests that TGFbeta1 could mediate, at least in part, the injury-induced upregulation of these isoforms.