K
Katherine R. Long
Researcher at Max Planck Society
Publications - 26
Citations - 842
Katherine R. Long is an academic researcher from Max Planck Society. The author has contributed to research in topics: Neocortex & Extracellular matrix. The author has an hindex of 11, co-authored 23 publications receiving 570 citations. Previous affiliations of Katherine R. Long include King's College London & University of Edinburgh.
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Journal ArticleDOI
Adhesion molecules in the stem cell niche – more than just staying in shape?
Véronique Marthiens,Ilias Kazanis,Lara Moss,Lara Moss,Katherine R. Long,Charles ffrench-Constant +5 more
TL;DR: Evidence is highlighted supporting a simple model whereby the regulation of centrosome positioning and spindle angle is regulated by both cadherins and integrins, and the differential activity of these two adhesion molecules enables the fundamental stem cell property of switching between asymmetrical and symmetrical divisions.
Journal ArticleDOI
How the extracellular matrix shapes neural development
TL;DR: This review considers how the ECM regulates cell shape, proliferation, differentiation and migration, and more recent work highlighting a key role of ECM in the morphogenesis of neural tissues.
Journal ArticleDOI
Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex.
Katherine R. Long,Ben Newland,Ben Newland,Marta Florio,Nereo Kalebic,Barbara Langen,Anna Kolterer,Pauline Wimberger,Wieland B. Huttner +8 more
TL;DR: This work investigates the potential role of ECM in the formation of neocortical folds and focuses on three specific ECM components localized in the human fetal cortical plate: hyaluronan and proteoglycan link protein 1, lumican and collagen I (collectively, HLC).
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Neocortical Expansion Due to Increased Proliferation of Basal Progenitors Is Linked to Changes in Their Morphology.
Nereo Kalebic,Carlotta Gilardi,Barbara K. Stepien,Michaela Wilsch-Bräuninger,Katherine R. Long,Takashi Namba,Marta Florio,Barbara Langen,Benoit Lombardot,Anna Shevchenko,Manfred W. Kilimann,Hiroshi Kawasaki,Pauline Wimberger,Wieland B. Huttner +13 more
TL;DR: In this article, the authors identify human membrane-bound PALMDELPHIN (PALMD-Caax) as an underlying factor, and show that it drives BP process growth and proliferation when expressed in developing mouse and ferret Ncx.
Journal ArticleDOI
Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex.
Nereo Kalebic,Carlotta Gilardi,Mareike Albert,Takashi Namba,Katherine R. Long,Milos Kostic,Barbara Langen,Wieland B. Huttner +7 more
TL;DR: Human-specific ARHGAP11B can elicit hallmarks of neocortical expansion in the developing ferret neocortex and exhibits increased neuron density in the upper cortical layers and expands in both the radial and tangential dimensions.