V. Matys

TL;DR: The TRANSFAC® database on transcription factors, their binding sites, nucleotide distribution matrices and regulated genes as well as the complementing database TRANSCompel® on composite elements have been further enhanced on various levels.

TL;DR: The TRANSFAC database on eukaryotic transcriptional regulation, comprising data on transcription factors, their target genes and regulatory binding sites, has been extended and further developed, both in number of entries and in the scope and structure of the collected data.

TL;DR: The TRANSFAC content has been enhanced by information about training sequences used for the construction of nucleotide matrices as well as by data on plant sites and factors, and the database has been extended by two new modules.

TL;DR: The TRANSFAC database on transcription factors and their DNA-binding sites and profiles has been quantitatively extended and supplemented by a number of modules that give information about pathologically relevant mutations in regulatory regions and transcription factor genes (PathoDB), scaffold/matrix attached regions (S/MARt DB), signal transduction and gene expression sources (CYTOMER).

TL;DR: Genes whose expression is regulated by a ligand-activated transcription factor, aryl hydrocarbon receptor (AhR), that mediates responses to a variety of toxins are studied.