Frank Schacherer

TL;DR: The TRANSFAC content has been enhanced by information about training sequences used for the construction of nucleotide matrices as well as by data on plant sites and factors, and the database has been extended by two new modules.

TL;DR: The TRANSFAC database on transcription factors and their DNA-binding sites and profiles has been quantitatively extended and supplemented by a number of modules that give information about pathologically relevant mutations in regulatory regions and transcription factor genes (PathoDB), scaffold/matrix attached regions (S/MARt DB), signal transduction and gene expression sources (CYTOMER).

TL;DR: Thousands of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases, and this large amount of pathway data in a computable form will support visualization, analysis and biological discovery.

TL;DR: In addition to being updated and extended by new features, it has been complemented now by a series of additional database modules, among them modules which provide data about signal transduction pathways (TRANSPATH) or about cell types/organs/developmental stages (CYTOMER) are available.

TL;DR: UNLABELLED TRANSPATH is an information system on gene-regulatory pathways, and an extension module to the TRANSFAC database system, that focuses on pathways involved in the regulation of transcription factors in different species, mainly human, mouse and rat.