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Valeria Covacci

Researcher at The Catholic University of America

Publications -  13
Citations -  755

Valeria Covacci is an academic researcher from The Catholic University of America. The author has contributed to research in topics: Intracellular & Cellular differentiation. The author has an hindex of 12, co-authored 13 publications receiving 729 citations. Previous affiliations of Valeria Covacci include Catholic University of the Sacred Heart.

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Y-TZP ceramics for artificial joint replacements

TL;DR: Samples made out Yttria coated powders show lower strength degradation than samples made out coprecipitated powders, and UHMWPE discs coupled to Y-TZP rings made out coated powder do not show increase in wear after repeated sterilization cycles of the ceramic rings.
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In vitro evaluation of the mutagenic and carcinogenic power of high purity zirconia ceramic.

TL;DR: It is shown that ceramic from high purity powders can be considered suitable for biomedical applications from the point of view of the effects of its radioactive impurity content, and the mutagenic and transforming effects of Y-TZP ceramic are demonstrated.
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Regulation of cell cycle progression and apoptosis by beta-carotene in undifferentiated and differentiated HL-60 leukemia cells: possible involvement of a redox mechanism.

TL;DR: Evidence is provided that β‐carotene modulates molecular pathways involved in cell cycle progression and apoptosis and support the hypothesis that a redox mechanism may be implicated and suggest that differentiated cells may be less susceptible to the carotenoid than highly neoplastic undifferentiated cells.
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Oxidative DNA damage as a marker of aging in WI-38 human fibroblasts.

TL;DR: Results lend support to the concept that oxidative stress may be a key determinant of aging by demonstrating that DNA damage in old/58 PDs cells reflects both an increased susceptibility to oxidative stress and a reduced efficiency of repair mechanisms.
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DNA oxidative damage during differentiation of HL-60 human promyelocytic leukemia cells.

TL;DR: In this article, DNA oxidative damage was measured in human promyelocytic leukemia HL-60 cells, in the same cells committed to granulocytic differentiation with dimethyl sulfoxide (DMSO) or all-trans-retinoic acid (RA) and in mature human peripheral granulocytes (HPG).