Showing papers by "Valérie Collot published in 2010"
TL;DR: In this paper, a Suzuki type cross coupling reaction of 3-iodoindazoles with aryl and heteroaryl boronic acids is described as a general route to 3-aryl indazoles.
Abstract: This paper describes a Suzuki Type cross coupling reaction of 3-iodoindazoles with aryl and heteroaryl boronic acids as a general route to 3-arylindazoles. The coupling reaction is illustrated by the preparation of new aryl- or heteroarylindazoles 7. Scope and limitation of the method are outlined. The coupling reaction works best on a 1-substituted indazole nucleus. The usefulness of the reaction is illustrated by a short practical synthesis of YC-1, a pharmacological agent potentialy useful for the treatment of cardiovascular diseases or erectile dysfunction.
2 citations
TL;DR: In this paper, the authors proposed a method for regioselective catalytic hydrogenation of N-acyl 3-phenylindole-2-carboxylates, which can be considered as phenylalanine semi-rigid derivatives.
Abstract: Regioselective catalytic hydrogenation of N-acyl 3-phenylindole-2-carboxylates is the key step for the preparation of cis and trans indoline-2-carboxamides which can be considered as phenylalanine semi-rigid derivatives. © 1997 Published by Elsevier Science Ltd.