V
Valérie Collot
Researcher at University of Caen Lower Normandy
Publications - 51
Citations - 647
Valérie Collot is an academic researcher from University of Caen Lower Normandy. The author has contributed to research in topics: Coupling reaction & Indazole. The author has an hindex of 14, co-authored 50 publications receiving 623 citations. Previous affiliations of Valérie Collot include Centre national de la recherche scientifique.
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Suzuki-type cross-coupling reaction of 3-iodoindazoles with aryl boronic acids: A general and flexible route to 3-arylindazoles
TL;DR: A Suzuki Type cross coupling reaction of 3-iodoindazoles with aryl and heteroaryl boronic acids with usefulness and usefulness illustrated by a short practical synthesis of YC-1, a pharmacological agent potentially useful for the treatment of cardiovascular diseases or erectile dysfunction.
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First combined selective N- and C-arylations with boronic acids: application to the synthesis of 1,3-diarylindazoles
TL;DR: 3-Iodoindazole as discussed by the authors allows combined N1- and C3-arylations with boronic acids, and can be combined in a one-pot procedure.
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Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles.
Pascale Schumann,Valérie Collot,Yannick Hommet,Willy Gsell,François Dauphin,Jana Sopkova,Eric T. MacKenzie,Dominique Duval,Michel Boulouard,Sylvain Rault +9 more
TL;DR: The synthesis and pharmacological evaluation of methoxyindazoles as new inhibitors of neuronal nitric oxide synthase are presented and it is shown that the nitro-substitution is not indispensable to the biological activity of the indazole ring.
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An Efficient Two-Step Total Synthesis of the Quaterpyridine Nemertelline
Alexandre Bouillon,Anne Sophie Voisin,Audrey Robic,Jean-Charles Lancelot,Valérie Collot,Sylvain Rault +5 more
TL;DR: Regioselective and univocal Suzuki cross-coupling reactions performed on halopyridinyl boronic acids provide a flexible and versatile route to a multigram scale synthesis of nemertelline, the quaterpyridine neurotoxin isolated from a Hoplonemertine sea worm.
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Sequential Sonogashira and Suzuki Cross-Coupling Reactions in the Indole and Indazole Series
Bernhard Witulski,Javier Ramon Azcon,Carole Alayrac,Anca Arnautu,Valérie Collot,Sylvain Rault +5 more
TL;DR: Three 5-bromo-3-iodoindoles and two indazoles have been studied with respect to their reactivity and selectivity in palladium catalyzed Sonogashira and Suzuki cross-coupling reactions to obtain a large range of new functionalized indoles and indazole ligands, which are potential 5-HT receptor ligands.