Valérie Dekimpe

TL;DR: This work demonstrates that the QS hierarchy is more complex than the model simply presenting the las system above the rhl system, and P. aeruginosa is able to circumvent the deficiency of one of its QS systems by allowing the other to take over.

TL;DR: Results indicate that only HAQs bearing a methyl group (HMAQs) are involved in quorum-sensing regulation, mainly because of their role as signaling molecules in Pseudomonas aeruginosa.

TL;DR: It is demonstrated that octanoic acid is directly incorporated into HHQ, the direct precursor of PQS, and uncovers promising targets for the development of specific antivirulence drugs to combat this opportunistic pathogen.

TL;DR: This work exhaustively surveyed the extracellular enzymes, siderophores, toxins, antimicrobials, and other secondary metabolites produced by the members of this very diverse genus Burkholderia.

TL;DR: A volatile, low molecular weight molecule produced by the opportunistic human pathogen Pseudomonas aeruginosa that reduces bacterial virulence in vivo in flies and in an acute mouse infection model is identified and it is proposed that 2-AA mediates changes in a subpopulation of cells that facilitate the exploitation of dynamic host environments and promote gene expression changes that favor chronic infections.