V
Valerie Fadok
Researcher at Anschutz Medical Campus
Publications - 2
Citations - 346
Valerie Fadok is an academic researcher from Anschutz Medical Campus. The author has contributed to research in topics: Kinase & Apoptosis. The author has an hindex of 2, co-authored 2 publications receiving 319 citations.
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Journal ArticleDOI
Oxidative Stress in Type 1 Diabetes
Kathryn Haskins,Brenda Bradley,Katherine Powers,Valerie Fadok,Sonia C. Flores,Xiaofeng Ling,Subbiah Pugazhenthi,Jane E.B. Reusch,Jennifer A. Kench +8 more
TL;DR: It is demonstrated that treatment of prediabetic NOD mice for 2 weeks with a metalloporphyrin superoxide dismutase (SOD) mimetic results in marked reduction of oxidative stress in islets and vascular tissue and a reversal of macrophage defects.
Journal ArticleDOI
Differential Roles for αMβ2 Integrin Clustering or Activation in the Control of Apoptosis via Regulation of Akt and ERK Survival Mechanisms
TL;DR: β2-integrin engagement can both delay and enhance apoptosis in the same cell, suggesting that integrins can play a dual role in the apoptotic progression of leukocytes.