V
Valérie Letscher-Bru
Researcher at University of Strasbourg
Publications - 66
Citations - 3133
Valérie Letscher-Bru is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Aspergillosis & Amphotericin B. The author has an hindex of 27, co-authored 58 publications receiving 2743 citations. Previous affiliations of Valérie Letscher-Bru include Louis Pasteur University & French Institute of Health and Medical Research.
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Journal ArticleDOI
Aspergillus galactomannan detection in the diagnosis of invasive aspergillosis in cancer patients.
Raoul Herbrecht,Valérie Letscher-Bru,Corina Oprea,Bruno Lioure,J. Waller,Odile Villard,Kun-Lun Liu,Shanti Natarajan-Amé,Patrick Lutz,Patrick Dufour,Jean-Pierre Bergerat,Ermanno Candolfi +11 more
TL;DR: Galactomannan ELISA seems less sensitive than previously described, and sensitivity can be further reduced by the presence of anti-Aspergillus antibodies.
Journal ArticleDOI
Factors Associated with Overall and Attributable Mortality in Invasive Aspergillosis
Yasmine Nivoix,Michel Velten,Valérie Letscher-Bru,Alireza Moghaddam,Shanti Natarajan-Amé,Cécile Fohrer,Bruno Lioure,Karin Bilger,Philippe Lutun,Luc Marcellin,Anne Launoy,Guy Freys,Jean-Pierre Bergerat,Raoul Herbrecht +13 more
TL;DR: Kohno et al. as discussed by the authors retrospectively reviewed 385 cases of suspected or documented aspergillosis that occurred during a 9-year period and identified 289 episodes that fulfilled the criteria for possible, probable, or proven invasive Aspergillus active antifungal drug treatment.
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Caspofungin: the first representative of a new antifungal class
TL;DR: Data in vitro, and experimental studies, have demonstrated that caspofungin has antifungal activity against yeasts of the genus Candida, several species of filamentous fungi, and certain dimorphic fungi, such as Histoplasma, Blastomyces and Coccidioides.
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Early diagnosis and monitoring of mucormycosis by detection of circulating DNA in serum: retrospective analysis of 44 cases collected through the French Surveillance Network of Invasive Fungal Infections (RESSIF)
Laurence Millon,Raoul Herbrecht,Frédéric Grenouillet,Florent Morio,Alexandre Alanio,Valérie Letscher-Bru,Sophie Cassaing,Taieb Chouaki,C. Kauffmann-Lacroix,Philippe Poirier,Dominique Toubas,O. Augereau,Steffi Rocchi,Dea Garcia-Hermoso,Stéphane Bretagne +14 more
TL;DR: It is shown that Mucorales quantitative PCR could not only confirm the mucormycosis diagnosis when other mycological arguments were present but could also anticipate this diagnosis.
Journal ArticleDOI
Treatment of 21 cases of invasive mucormycosis with amphotericin B colloidal dispersion.
Raoul Herbrecht,Valérie Letscher-Bru,Raleigh A. Bowden,Shimon Kusne,Elias Anaissie,John R. Graybill,Gary A. Noskin,Beryl A. Oppenheim,Emmanuel Andrès,L. Pietrelli +9 more
TL;DR: Results compare favourably with the results of standard treatment and suggest that ABCD combined with surgery may be a useful therapy in patients with mucormycosis.