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Vanessa de Andrade Royo

Researcher at Unimontes

Publications -  59
Citations -  557

Vanessa de Andrade Royo is an academic researcher from Unimontes. The author has contributed to research in topics: Population & Genetic structure. The author has an hindex of 11, co-authored 51 publications receiving 479 citations. Previous affiliations of Vanessa de Andrade Royo include University of São Paulo.

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In vivo analgesic and anti-inflammatory activities of ursolic acid and oleanoic acid from Miconia albicans (Melastomataceae).

TL;DR: It is suggested that other compounds, rather than UA and OA, should be responsible for the evaluated activities in the crude extract of Miconia albicans aerial parts, since the crude Extract samples displayed good activities.
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Trypanocidal activity of (-)-cubebin derivatives against free amastigote forms of Trypanosoma cruzi.

TL;DR: Five (-)-cubebin derivative compounds, (-)-O-acetyl cubebin (3), (-)-N,N-dimethylaminoethyl-cub Pastebin (5), (--hinokinin (6) and (-)-6,6'-dinitrohinokin in (7), previously synthesised by the research group, were evaluated on in vitro assay against free amastigote forms of Trypanosoma cruzi.
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Evaluation of piper cubeba extract, (-)-cubebin and its semi-synthetic derivatives against oral pathogens.

TL;DR: The semi‐synthetic derivative of (‐)‐6,6′‐dinitrohinokinin was the most active compound against all the evaluated microorganisms and it may be suggested that the presence of the carbonyl group at C‐9 plus the introduction of polar groups in the aromatic rings improve the antimicrobial activity of dibenzylbutyrolactone compounds.
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Hinokinin causes antigenotoxicity but not genotoxicity in peripheral blood of Wistar rats.

TL;DR: The present study shows that (-)-hinokinin not only has no genotoxic effect, but is also effective in reducing the chromosome damage induced by the chemotherapeutic agent doxorubicin (DXR).