Vazhaikkurichi M. Rajendran

TL;DR: This work determined whether anion exchange isoforms (AE) and/or downregulated in adenoma (DRA) are expressed in and related to apical membrane anion exchanges by examining localization of AE isoform-specific and DRA mRNA expression in normal and Na-depleted rats.

TL;DR: The results suggest that the r SK4 channel mediates K+ secretion induced by muscarinic agonists in the rat proximal colon and that transcription of the rSK4 channel is downregulated to prevent K+ loss during dietary K+ depletion.

TL;DR: Differential effects by sodium depletion on Na+/H+exchange in rat colon are tissue specific and isoform specific; sodium depletion both induces and inhibits apical Na-/H-exchange at a pretranslational level.

TL;DR: It is concluded that exosomes might override the ECM mediated instructive signals during lineage specification of hMSCs, as shown in the example of osteoblast/adipocyte ECM and exosome combination.

TL;DR: Results indicate that CT has varying effects on the two apical NHE isoforms, inhibiting NHE2 activity without altering its protein expression and reducing both NHE3 activity and protein expression.