V
Vera Borges
Researcher at Sao Paulo State University
Publications - 75
Citations - 1157
Vera Borges is an academic researcher from Sao Paulo State University. The author has contributed to research in topics: Preeclampsia & Pregnancy. The author has an hindex of 16, co-authored 74 publications receiving 921 citations. Previous affiliations of Vera Borges include Universidade Nova de Lisboa & University of Lisbon.
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Journal ArticleDOI
Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia.
Ingrid C. Weel,Rebecca N. Baergen,Mariana Romao-Veiga,Vera Borges,Vanessa Rocha Ribeiro,Steven S. Witkin,Camila F. Bannwart-Castro,José Carlos Peraçoli,Leandro Gustavo de Oliveira,Maria Terezinha Serrão Peraçoli +9 more
TL;DR: The more severe lesions and the imbalance between TNF-α/IL-10 and PlGF/sFlt-1 in placentas from early-onset PE allows differentiation of early and late-onsets PE and suggests higher placental impairment in early-ONSet PE.
Journal ArticleDOI
Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia.
Mariana Leticia Matias,Mariana Romao,Ingrid C. Weel,Vanessa Rocha Ribeiro,Priscila Rezeck Nunes,Vera Borges,João Pessoa Araújo,José Carlos Peraçoli,Leandro Gustavo de Oliveira,Maria Terezinha Serrão Peraçoli +9 more
TL;DR: Increased basal gene expression of NLRP1 and NLRP3 receptors in monocytes from PE group demonstrates that uric acid plays a role inNLRP3 inflammasome activation, suggesting the participation of this inflammatory complex in the pathogenesis of preeclampsia.
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Increased expression of NLRP3 inflammasome in placentas from pregnant women with severe preeclampsia.
Ingrid C. Weel,Mariana Romao-Veiga,Mariana Leticia Matias,E. G. Fioratti,José Carlos Peraçoli,Vera Borges,João Pessoa Araújo,Maria Terezinha Serrão Peraçoli +7 more
TL;DR: The results suggest that placentas from pregnant women with preeclampsia show higher expression of NLRP3 inflammasome, which may be involved in the exaggerated inflammatory state in preeClampsia.
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Association between cytokine profile and transcription factors produced by T-cell subsets in early- and late-onset pre-eclampsia.
Vanessa Rocha Ribeiro,Mariana Romao-Veiga,Graziela Gorete Romagnoli,Mariana Leticia Matias,Priscila Rezeck Nunes,Vera Borges,José Carlos Peraçoli,Maria Terezinha Serrão Peraçoli +7 more
TL;DR: The results show that in women with PE there is an imbalance between inflammatory and anti‐inflammatory profiles in CD4+ T‐cell subsets, with polarization to Th17 profiles in the early‐onset PE, considered as the severe form of PE.
Journal ArticleDOI
High levels of heat shock protein 70 are associated with pro-inflammatory cytokines and may differentiate early- from late-onset preeclampsia.
José Carlos Peraçoli,Camila F. Bannwart-Castro,Mariana Romao,Ingrid C. Weel,Vanessa Rocha Ribeiro,Vera Borges,Marilza Vieira Cunha Rudge,Steven S. Witkin,Maria Terezinha Serrão Peraçoli +8 more
TL;DR: Early-onset PE was associated with greater maternal and fetal impairment and there were positive correlations between Hsp70 levels and TNF-α, TNFRI, IL-1β,IL-12, GOT, GPT, LDH, and uric acid concentrations in early-ONSet PE group.