Vicky Jespers

TL;DR: It is conclusively shown that lactobacilli-dominated VMB are associated with a healthy vaginal micro-environment and that bacterial vaginosis (BV) is best described as a polybacterial dysbiosis.

TL;DR: It is shown that the quantification of specific bacteria by qPCR contributes to a better description of the non-BV vaginal microbiome, but it is demonstrated that differences in populations such as risk and ethnicity also have to be taken into account.

TL;DR: The contribution of vaginal dysbiosis to the global burden of other dysbiotic states of importance to global health are vaginal microbiota with a high abundance of streptococci, staphylococci or Enterobacteriaceae, vaginal candidiasis and trichomoniasis, and areas that require more research are highlighted.

TL;DR: This longitudinal study confirms the inflammatory nature of vaginal dysbiosis and its association with recent vaginal sex and progestin-injectable use and a potential role for proinflammatory mediators and IP-10 in combination with the vaginal-health-score as predictive biomarkers for vaginal Dysbiosis merits further investigation.

TL;DR: Data in support of the hypothesis that variations in per sex-act transmission probability of HIV may in part be attributed to differences in the composition and function of the vaginal microbiota between different populations are presented.