V
Vijay Mohan K. Namboodiri
Researcher at University of Washington
Publications - 27
Citations - 1338
Vijay Mohan K. Namboodiri is an academic researcher from University of Washington. The author has contributed to research in topics: Optogenetics & Orbitofrontal cortex. The author has an hindex of 14, co-authored 27 publications receiving 928 citations. Previous affiliations of Vijay Mohan K. Namboodiri include University of North Carolina at Chapel Hill & University of California, San Francisco.
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Journal ArticleDOI
Prefrontal cortex output circuits guide reward seeking through divergent cue encoding
James M. Otis,Vijay Mohan K. Namboodiri,Ana M. Matan,Elisa S. Voets,Emily P. Mohorn,Oksana Kosyk,Jenna A. McHenry,J. Elliott Robinson,Shanna L. Resendez,Mark A. Rossi,Garret D. Stuber +10 more
TL;DR: In vivo two-photon calcium imaging is used to monitor the activity of dorsomedial prefrontal neurons in mice during an appetitive Pavlovian conditioning task to show how prefrontal circuitry can dynamically control reward-seeking behaviour through the opposing activities of projection-specific cell populations.
Journal ArticleDOI
Visualization of cortical, subcortical and deep brain neural circuit dynamics during naturalistic mammalian behavior with head-mounted microscopes and chronically implanted lenses
Shanna L. Resendez,Josh H Jennings,Randall L. Ung,Vijay Mohan K. Namboodiri,Zhe Charles Zhou,James M. Otis,Hiroshi Nomura,Jenna A. McHenry,Oksana Kosyk,Garret D. Stuber +9 more
TL;DR: These limitations can be circumvented by using miniature, integrated microscopes in conjunction with an implantable microendoscopic lens to guide light into and out of the brain, thus permitting optical access to deep brain (or superficial) neural ensembles during naturalistic behaviors.
Journal ArticleDOI
Paraventricular Thalamus Projection Neurons Integrate Cortical and Hypothalamic Signals for Cue-Reward Processing.
James M. Otis,Manhua Zhu,Vijay Mohan K. Namboodiri,Cory A. Cook,Oksana Kosyk,Ana M. Matan,Rose Ying,Yoshiko Hashikawa,Koichi Hashikawa,Ivan Trujillo-Pisanty,Jiami Guo,Randall L. Ung,Jose Rodriguez-Romaguera,E.S. Anton,Garret D. Stuber +14 more
TL;DR: Using in-vivo two-photon calcium imaging, it is found that PVT neurons projecting to the nucleus accumbens (PVT-NAc) develop inhibitory responses to reward-predictive cues coding for both cue-reward associative information and behavior.
Journal ArticleDOI
Single-cell activity tracking reveals that orbitofrontal neurons acquire and maintain a long-term memory to guide behavioral adaptation
Vijay Mohan K. Namboodiri,Vijay Mohan K. Namboodiri,James M. Otis,James M. Otis,Kay van Heeswijk,Kay van Heeswijk,Elisa S. Voets,Rizk A. Alghorazi,Jose Rodriguez-Romaguera,Stefan Mihalas,Garret D. Stuber +10 more
TL;DR: It is revealed that orbitofrontal cortex acquires and maintains a long-term memory of cue–reward associations to guide multiple aspects of behavioral learning, and that it routes select information to a downstream learning center.
Journal ArticleDOI
Social Stimuli Induce Activation of Oxytocin Neurons Within the Paraventricular Nucleus of the Hypothalamus to Promote Social Behavior in Male Mice.
Shanna L. Resendez,Vijay Mohan K. Namboodiri,James M. Otis,Louisa E.H. Eckman,Jose Rodriguez-Romaguera,Randall L. Ung,Marcus L. Basiri,Oksana Kosyk,Mark A. Rossi,Gabriel S. Dichter,Garret D. Stuber +10 more
TL;DR: It is shown that chemogenetic activation of OT neurons within the paraventricular nucleus of the hypothalamus (PVH) of male mice (OT-Ires-Cre) enhanced social investigation during a social choice test, while Chemogenetic inhibition of these neurons abolished typical social preferences, suggesting that activation of the OT system is necessary to direct behavior preferentially toward social stimuli.