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Viktor Johanson

Researcher at University of Gothenburg

Publications -  37
Citations -  1126

Viktor Johanson is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Somatostatin receptor & Somatostatin. The author has an hindex of 20, co-authored 36 publications receiving 998 citations. Previous affiliations of Viktor Johanson include Sahlgrenska University Hospital.

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A Transplantable Human Carcinoid as Model for Somatostatin Receptor-Mediated and Amine Transporter-Mediated Radionuclide Uptake

TL;DR: A human midgut carcinoid tumor was successfully transplanted into nude mice and propagated for five consecutive generations (30 months) with well-preserved phenotype as discussed by the authors, and the human origin of transplanted tumor cells was confirmed by cytogenetic and fluorescence it situ hybridization analyses.
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Uptake of meta-iodobenzylguanidine in neuroendocrine tumours is mediated by vesicular monoamine transporters.

TL;DR: VMATs and secretory granules are of importance for the uptake and retention of 123I-MIBG in NE tumours and information about the type and degree of expression of VMATs may be helpful in future to select patients suitable for radiation therapy with radio-iodinated MIBG.
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Internalization of indium-111 into human neuroendocrine tumor cells after incubation with indium-111-DTPA-D-Phe1-octreotide

TL;DR: Indium-111 DTPA-D-Phe1-octreotide might be useful for radiation therapy of patients with surgically incurable tumors having high somatostatin receptor densities.
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Prognostic factors for survival after surgery for adrenal metastasis

TL;DR: Surgery for adrenal metastasis is safe and the indication for this procedure in an individual patient can be supported by several prognostic factors, and the survival benefit in patients with adrenalectomy for potential cure indicates a therapeutic value of Adrenalectomy in selected patients.
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The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.

TL;DR: A large-scale inhibitor screening showed that cell lines from pancreatic NETs to a greater extent, when compared to small intestinal NETs, were sensitive to inhibitors of MEK and neuroendocrine NET cells originating from the small intestine were considerably more sensitive to a group of HDAC inhibitors.