V
Vimala N. Bharadwaj
Researcher at Arizona State University
Publications - 14
Citations - 249
Vimala N. Bharadwaj is an academic researcher from Arizona State University. The author has contributed to research in topics: Traumatic brain injury & Medicine. The author has an hindex of 4, co-authored 11 publications receiving 147 citations. Previous affiliations of Vimala N. Bharadwaj include Stanford University & University of Arizona.
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Journal ArticleDOI
Nanoparticle-Based Therapeutics for Brain Injury.
TL;DR: The focus of this progress report is to provide a survey of NP strategies employed in cerebral ischemia and brain trauma and provide insights for improved NP‐based diagnostic/treatment approaches.
Journal ArticleDOI
Temporal assessment of nanoparticle accumulation after experimental brain injury: Effect of particle size.
Vimala N. Bharadwaj,Jonathan Lifshitz,Jonathan Lifshitz,P. David Adelson,P. David Adelson,Vikram D. Kodibagkar,Sarah E. Stabenfeldt +6 more
TL;DR: The accumulation of particles up to 500 nm at different times acutely after injury is characterized, indicating the potential of NP-based TBI theranostics in the acute period after injury.
Journal ArticleDOI
Blood-brainbarrier disruption dictates nanoparticle accumulation following experimental brain injury.
Vimala N. Bharadwaj,Rachel K. Rowe,Rachel K. Rowe,Rachel K. Rowe,Jordan L. Harrison,Chen Wu,Trent Anderson,Jonathan Lifshitz,P. David Adelson,P. David Adelson,Vikram D. Kodibagkar,Sarah E. Stabenfeldt +11 more
TL;DR: This study provides the groundwork for feasibility of NP-delivery based on NPinjection time and NPsize after mCHI/RmCHI and midline-FPI and shows that midlineFPI resulted in significant peak accumulation of up to 500 nm NP at 3 h post-injury compared to sham, 1 h, and 6 h groups in the cortex.
Journal ArticleDOI
Sex-Dependent Macromolecule and Nanoparticle Delivery in Experimental Brain Injury
Vimala N. Bharadwaj,Connor Copeland,Ethan Mathew,Jason M. Newbern,Trent Anderson,Jonathan Lifshitz,Jonathan Lifshitz,Vikram D. Kodibagkar,Sarah E. Stabenfeldt +8 more
TL;DR: A sex-dependent temporal profile of blood/brain barrier disruption in a preclinical mouse model of traumatic brain injury (TBI) that contributes to starkly different macromolecule and nanoparticle delivery profiles post-TBI is identified.
Journal ArticleDOI
Intranasal Administration for Pain: Oxytocin and Other Polypeptides
TL;DR: In this paper, the authors discuss the delivery of polypeptides to the peripheral and central nervous systems following intranasal (IN) administration and briefly discuss the mechanism of delivery via the nasal-cerebral pathway.