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Vimalkumar Velayudhan

Researcher at University College Cork

Publications -  7
Citations -  648

Vimalkumar Velayudhan is an academic researcher from University College Cork. The author has contributed to research in topics: Microbiome & Human virome. The author has an hindex of 6, co-authored 7 publications receiving 352 citations.

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Journal ArticleDOI

The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific

TL;DR: This study performed longitudinal metagenomic analysis of fecal viruses in healthy adults that reveal high temporal stability, individual specificity, and correlation with the bacterial microbiome.
Journal ArticleDOI

RiboGalaxy: A browser based platform for the alignment, analysis and visualization of ribosome profiling data.

TL;DR: RiboGalaxy is presented, a freely available Galaxy-based web server for processing and analyzing ribosome profiling data with the visualization functionality provided by GWIPS-viz, and offers researchers a suite of tools specifically tailored for processing ribo-seq and corresponding mRNA-seq data.
Posted ContentDOI

The human gut virome is highly diverse, stable and individual-specific

TL;DR: A longitudinal focused metagenomic study of faecal bacteriophage populations in healthy adults reveals the existence of a stable, numerically predominant individual-specific persistent personal virome which correlates with the bacterial microbiome.
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Comparative analysis of Faecalibacterium prausnitzii genomes shows a high level of genome plasticity and warrants separation into new species-level taxa

TL;DR: A very low level of average nucleotide identity among F. prausnitzii genomes is revealed and two genomogroups can be separated based on differences in functional gene complement, albeit that this division does not fully agree with separation based on conserved gene phylogeny.
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Autochthonous faecal viral transfer (FVT) impacts the murine microbiome after antibiotic perturbation

TL;DR: Given that bacteriophages are biologically inert in the absence of their host bacteria, they could form a safe and effective alternative to whole microbiota transplants that could be delivered during/following perturbation of the gut flora.