V
Vincent Fallet
Researcher at University of Paris
Publications - 68
Citations - 664
Vincent Fallet is an academic researcher from University of Paris. The author has contributed to research in topics: Medicine & Lung cancer. The author has an hindex of 11, co-authored 45 publications receiving 440 citations. Previous affiliations of Vincent Fallet include Pierre-and-Marie-Curie University.
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Journal ArticleDOI
Sarcomatoid lung carcinomas show high levels of programmed death ligand-1 (PD-L1) and strong immune-cell infiltration by TCD3 cells and macrophages
T. Vieira,Martine Antoine,Cécile Hamard,Vincent Fallet,Michael Duruisseaux,Nathalie Rabbe,Anita Rodenas,Jacques Cadranel,Marie Wislez +8 more
TL;DR: PD-L1 expression was higher in SC than in NSCLC as well as immune-cell infiltration by TCD3 cells and macrophages, suggesting that targeting the PD-1/PD- L1 pathway could represent a new potential therapy.
Journal ArticleDOI
High-throughput somatic mutation profiling in pulmonary sarcomatoid carcinomas using the LungCarta™ Panel: exploring therapeutic targets
Vincent Fallet,Raphaël Saffroy,Nicolas Girard,Julien Mazieres,Sylvie Lantuejoul,T. Vieira,Isabelle Rouquette,F. Thivolet-Bejui,Mony Ung,Virginie Poulot,L. Schlick,D. Moro-Sibilot,Martine Antoine,Jacques Cadranel,Antoinette Lemoine,Marie Wislez +15 more
TL;DR: Despite SC tumors exhibiting a high histological heterogeneity, some intratumoral molecular homogeneity was found and patients may be eligible for new target mutations, and can now therefore be screened for clinical trials.
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Pulmonary complications of immune checkpoint inhibitors in patients with nonsmall cell lung cancer
Jacques Cadranel,A. Canellas,Lise Matton,Marie Darrason,Antoine Parrot,Jean-Marc Naccache,Armelle Lavolé,Anne-Marie Ruppert,Vincent Fallet +8 more
TL;DR: This narrative review focuses on the epidemiology, clinical and radiological presentation and prognosis of ICI-P occurring in patients, especially those with advanced NSCLC and a proposal for pragmatic management, including differential diagnosis and therapeutic strategies, is presented.
Journal ArticleDOI
Blood vessel invasion is a major feature and a factor of poor prognosis in sarcomatoid carcinoma of the lung
T. Vieira,Martine Antoine,Anne-Marie Ruppert,Vincent Fallet,Michael Duruisseaux,Etienne Giroux Leprieur,Virginie Poulot,Nathalie Rabbe,Laurene Sclick,Michèle Beau-Faller,Roger Lacave,Armelle Lavolé,Jacques Cadranel,Marie Wislez +13 more
TL;DR: Dedifferentiation in NSCLC could lead to SC and an epithelial subtype component could influence outcome, and BVI was present in almost all SCs and was an independent factor of poor prognosis.
Journal ArticleDOI
Prospective screening for ALK: clinical features and outcome according to ALK status.
Vincent Fallet,Jacques Cadranel,Hélène Doubre,Cécile Toper,Isabelle Monnet,Thierry Chinet,G. Oliviero,Guillaume Foulon,Hubert de Cremoux,T. Vieira,Martine Antoine,Marie Wislez +11 more
TL;DR: Detailed clinico-pathological characteristics and outcomes of a cohort of French patients prospectively screened for Anaplastic Lymphoma Kinase (ALK) rearrangement found that French ALK+ patients present a specific phenotype.