V
Virginia Sandonis
Researcher at Carlos III Health Institute
Publications - 15
Citations - 285
Virginia Sandonis is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Viral evolution & Viral replication. The author has an hindex of 8, co-authored 14 publications receiving 222 citations. Previous affiliations of Virginia Sandonis include Hospital General Universitario Gregorio Marañón & University of Seville.
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Journal ArticleDOI
Coinfection and Superinfection in Patients with Long-Term, Nonprogressive HIV-1 Disease
Concepción Casado,Maria Pernas,Tamara Alvaro,Virginia Sandonis,S García,Carmen Rodríguez,Jorge del Romero,Eulalia Grau,Lidia Ruiz,Cecilio López-Galíndez +9 more
TL;DR: Dual infections occur in patients with long-term, nonprogressive HIV-1 disease, with no immediate clinical manifestations, which could indicate a general phenomenon in natural HIV- 1 infections.
Journal ArticleDOI
A combination of defective DNA and protective host factors are found in a set of HIV-1 ancestral LTNPs.
Virginia Sandonis,Concepción Casado,Tamara Alvaro,Maria Pernas,Isabel Olivares,S García,Carmen Rodríguez,Jorge del Romero,Cecilio López-Galíndez +8 more
TL;DR: Viral evolution in three HIV-1 ancestral patients from a group of LTNPs is studied; although some minor sequences showing viral evolution were detected in all patients, the extremely low viral evolution of their viruses was shown by the phylogenetic analysis of the env sequences.
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Comparison of real-time RT-PCR, shell vial culture, and conventional cell culture for the detection of the pandemic influenza A (H1N1) in hospitalized patients
Paula López Roa,Pilar Catalán,Maddalena Giannella,Darío García de Viedma,Virginia Sandonis,Emilio Bouza +5 more
TL;DR: Real-time RT-PCR displayed high sensitivity and specificity for the detection of influenza A H1N1 in adult patients when compared with conventional techniques, and the A549 cell line was not inferior to the MDCK line.
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A subset of human immunodeficiency virus type 1 long-term non-progressors is characterized by the unique presence of ancestral sequences in the viral population
Gonzalo Bello,Concepción Casado,Virginia Sandonis,M. Alonso‐Nieto,José Luis Vicario,S García,Victoria Hernando,Carmen Rodríguez,Jorge del Romero,Cecilio López-Galíndez +9 more
TL;DR: Dating of global populations and of DNA and RNA viral quasispecies identified two subsets of patients: one displaying only ancestral sequences and the other displaying predominantly modern sequences, which show very different virological, immunological, host and clinical-epidemiological characteristics.
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Plasma viral load threshold for sustaining intrahost HIV type 1 evolution.
Gonzalo Bello,Concepción Casado,Virginia Sandonis,Tamara Alvaro-Cifuentes,Caio A. Rodrigues dos Santos,S García,Carmen Rodríguez,Jorge del Romero,José Henrique Pilotto,Beatriz Grinsztejn,Valdilea G. Veloso,Mariza G. Morgado,Cecilio López-Galíndez +12 more
TL;DR: The results suggest that the detection limit of ultrasensitive viremia assays could represent an important threshold below which intrahost HIV-1 evolution does not occur.