L
Lidia Ruiz
Researcher at Foundation University, Islamabad
Publications - 137
Citations - 7820
Lidia Ruiz is an academic researcher from Foundation University, Islamabad. The author has contributed to research in topics: Viral load & Drug resistance. The author has an hindex of 48, co-authored 136 publications receiving 7387 citations.
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Journal ArticleDOI
Prevalence of Drug-Resistant HIV-1 Variants in Untreated Individuals in Europe: Implications for Clinical Management
Annemarie M. J. Wensing,David A. M. C. van de Vijver,Gioacchino Angarano,Birgitta Åsjö,Claudia Balotta,Enzo Boeri,Ricardo Jorge Camacho,Maire-Laure Chaix,Dominique Costagliola,Andrea De Luca,Inge Derdelinckx,Zehava Grossman,Osamah Hamouda,Angelos Hatzakis,Robert Hemmer,Andy I. M. Hoepelman,Andrzej Horban,Klaus Korn,Claudia Kücherer,Thomas Leitner,Clive Loveday,E MacRae,I Maljkovic,Carmen de Mendoza,Laurence Meyer,Claus J. Nielsen,Eline L. M. Op de Coul,Vidar Ormaasen,D Paraskevis,Luc Perrin,Elisabeth Puchhammer-Stöckl,Lidia Ruiz,Mika Salminen,Jean-Claude Schmit,François Schneider,Rob Schuurman,Vincent Soriano,G Stanczak,Maja Stanojevic,Anne-Mieke Vandamme,Kristel Van Laethem,Michela Violin,Karin Wilbe,Sabine Yerly,Maurizio Zazzi,Charles A. Boucher +45 more
TL;DR: In this paper, the authors determined the baseline rate of drug resistance in 2208 therapy-naive patients recently and chronically infected with HIV-1 from 19 European countries during 1996-2002.
Journal ArticleDOI
Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection.
Rika Draenert,Sylvie Le Gall,Katja Pfafferott,Alasdair Leslie,Polan Chetty,Christian Brander,Edward C. Holmes,Shih-Chung Chang,Margaret E. Feeney,Marylyn M. Addo,Lidia Ruiz,Danni Ramduth,P M Jeena,Marcus Altfeld,Stephanie Thomas,Yanhua Tang,Cori L. Verrill,Catherine Dixon,Julia G. Prado,Photini Kiepiela,Javier Martinez-Picado,Bruce D. Walker,Philip J. R. Goulder,Philip J. R. Goulder +23 more
TL;DR: It is demonstrated that allele-associated sequence variation within the flanking region of CTL epitopes can alter antigen processing and is of major relevance in the construction of vaccine sequences.
Journal ArticleDOI
Clinical utility of HIV-1 genotyping and expert advice: the Havana trial.
Cristina Tural,Lidia Ruiz,Christopher Holtzer,Jonathan M. Schapiro,Pompeyo Viciana,Juan R. González,Pere Domingo,Charles A. Boucher,Celestino Rey-Joly,Bonaventura Clotet +9 more
TL;DR: HIV-1 genotyping interpreted by a software package improves the virological outcome when it is added to the clinical information as a basis for decisions on changing antiretroviral therapy.
Journal ArticleDOI
Prospective randomized two-Arm controlled study to determine the efficacy of a specific intervention to improve long-term adherence to highly active antiretroviral therapy.
Albert Tuldrà,Carmina R. Fumaz,Ma José Ferrer,Ramon Bayes,A. Arnó,Montserrat Balagué,Anna Bonjoch,Antoni Jou,Eugenia Negredo,Roger Paredes,Lidia Ruiz,Joan Romeu,Guillem Sirera,Cristina Tural,David M. Burger,Bonaventura Clotet +15 more
TL;DR: Assessment of certain specific variables related to adherence may be helpful to monitor patient's compliance in the clinical setting and specific and maintained psychoeducative interventions based on excellence on clinical practice are useful to keep high levels of adherence as well as high levelsof viral suppression.
Journal ArticleDOI
Human cytomegalovirus infection is associated with increased proportions of NK cells that express the CD94/NKG2C receptor in aviremic HIV-1-positive patients.
Monica Guma,Cecilia Cabrera,Itziar Erkizia,Margarita Bofill,Bonaventura Clotet,Lidia Ruiz,Miguel López-Botet +6 more
TL;DR: The conclusion that changes in the NKR repertoire in HIV1-positive patients are related to a concomitant HCMV infection is supported.