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W.J.F. van der Vijgh
Researcher at VU University Amsterdam
Publications - 155
Citations - 9743
W.J.F. van der Vijgh is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Pharmacokinetics & Carboplatin. The author has an hindex of 45, co-authored 155 publications receiving 9419 citations. Previous affiliations of W.J.F. van der Vijgh include Maastricht University Medical Centre & VU University Medical Center.
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Structural aspects of antioxidant activity of flavonoids.
TL;DR: It can be concluded that Ep/2 values and iron chelating activity can almost completely describe the LPO inhibiting behaviour of the flavonoids.
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Structural aspects of antioxidant activity of flavonoids.
S.A.B.E. van Acker,D.-J. Van Den Berg,M. N. J. L. Tromp,D. H. Griffioen,W.P. van Bennekom,W.J.F. van der Vijgh,Aalt Bast +6 more
TL;DR: In this article, a large group of flavonoids from all major structural subclasses were tested on their ability to inhibit doxorubicin (enzymatically)-induced microsomal lipid peroxidation (LPO) and to chelate Fe2+.
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Prevention of Bone Loss by Vitamin D Supplementation in Elderly Women: A Randomized Double-Blind Trial*
TL;DR: In this article, the effect of vitamin D supplementation on bone turnover and bone loss in elderly women was evaluated by a double-blind, randomized study, and the effect was expressed as the difference in mean (percentage) change between the placebo group and the vitamin D group.
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A quantum chemical explanation of the antioxidant activity of flavonoids.
S.A.B.E. van Acker,M.J. de Groot,D.-J. Van Den Berg,M. N. J. L. Tromp,G. M. Donne-Op Den Kelder,W.J.F. van der Vijgh,Aalt Bast +6 more
TL;DR: By comparing the geometries of several flavonoids, this work was able to explain the structural dependency of the antioxidant action of these compounds and investigate the spin density of the radical to determine the delocalization possibilities.
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The Effect of Vitamin D Supplementation on Vitamin D Status and Parathyroid Function in Elderly Subjects
Paul Lips,A. Wiersinga,F.C. van Ginkel,M. J. M. Jongen,J. C. Netelenbos,Wil H.L. Hackeng,Pierre D. Delmas,W.J.F. van der Vijgh +7 more
TL;DR: It is concluded that a vitamin D3 supplement of 400 IU/day adequately improves vitamin D status in elderly people and increases 1,25-dihydroxyvitamin D concentrations in those with vitamin D deficiency.