W.W. Mapleson

TL;DR: Regression analysis showed that data for humans derived from a comprehensive literature survey were consistent, for age > 1 yr, with log10 MAC decreasing with increasing age at the same rate for all inhaled anaesthetics; approximately equivalent to 6% change per decade of age.

TL;DR: The iso-MAC charts show clearly how patient age can be used to guide the choice of end-expired agent concentration and allow a consistent total MAC to be maintained when changing the inspired nitrous oxide concentration, thereby reducing the chance of inadvertent awareness, particularly at the extremes of age.

TL;DR: It is recommended that anaesthetists make their own assessments of Mallampati classification, with the patient in either of the postures but always either with or without phonation, and thereby gradually "calibrate" their assessments against the degree of difficulty encountered in intubation.

TL;DR: In a randomised cross‐over study, 48 anaesthetists attempted to place a Frova single‐use introducer, an Eschmann multiple‐use Introducer and a Portex single‐ use introducer in the trachea of a manikin set up to simulate a grade 3 laryngoscopic view, indicating that the single‐used introducers are more likely to cause tissue trauma during placement.

TL;DR: It was found that clonidine and dexmedetomidine strongly inhibited gastrointestinal transit and morphine significantly inhibited gastric emptying, but the effect was weak and naloxone, which significantly antagonized the effect of morphine, did not antagonize theeffect of either of the other agonists.