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Showing papers by "Wafaa S. Hamama published in 2000"


Journal ArticleDOI
TL;DR: In this paper, the Mannich type reaction using aminals was used to obtain the primary base of 1-aminomethyl-2,3-dihydro-1H-benzo[d]imidazole-2-thione.
Abstract: ). On the other hand, treatment of 1 with formalin anddimethylamine in molar ratio of (1:2:2) afforded the bis-base3.The primary base, 1-aminomethyl-2,3-dihydro-1H-benzo[d]imidazole-2-thione (4) was prepared through thereaction of 1 with formalin and urotropine in acidic medium.However, compound 4 cannot be obtained if ammonia is usedin lieu of urotropine. Formation of 4 is in line with thereported Mannich type reaction using aminals.

6 citations