W
Wai-Yee Leung
Researcher at Molecular Probes
Publications - 21
Citations - 1985
Wai-Yee Leung is an academic researcher from Molecular Probes. The author has contributed to research in topics: Fluorescence & Electroblotting. The author has an hindex of 12, co-authored 21 publications receiving 1910 citations. Previous affiliations of Wai-Yee Leung include Life Technologies.
Papers
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Journal ArticleDOI
Alexa Dyes, a Series of New Fluorescent Dyes that Yield Exceptionally Bright, Photostable Conjugates:
Nataliya Panchuk-Voloshina,Rosaria P. Haugland,Janell Bishop-Stewart,Mahesh K. Bhalgat,Paul J. Millard,Fei Mao,Wai-Yee Leung,Richard P. Haugland +7 more
TL;DR: This work evaluated Alexa dyes compared with conventional dyes in applications using various conjugates, including those of goat anti-mouse IgG (GAM), streptavidin, wheat germ agglutinin (WGA), and concanavalin A (ConA).
Journal ArticleDOI
Global quantitative phosphoprotein analysis using Multiplexed Proteomics technology
Thomas H. Steinberg,Brian Agnew,Kyle R. Gee,Wai-Yee Leung,Terrie Goodman,Birte Schulenberg,Jill Hendrickson,Joseph M. Beechem,Richard P. Haugland,Wayne F. Patton +9 more
TL;DR: This evolving discovery platform allows the parallel determination of protein expression level changes and altered post‐translational modification patterns within a single 2‐D gel experiment, and the linear responses of the fluorescence dyes utilized, allow rigorous quantitation of changes over an unprecedented 500-fold concentration range.
Patent
Sulfonated xanthene derivatives
TL;DR: In this paper, the present invention describes xanthene dyes, including rhodamines, rhodols and fluoresceins that are substituted one or more times by a sulfonic acid or a salt of a sulphonic acid.
Journal ArticleDOI
Detection of glycoproteins in polyacrylamide gels and on electroblots using Pro-Q Emerald 488 dye, a fluorescent periodate Schiff-base stain.
TL;DR: The green‐fluorescent signal from Pro‐Q Emerald 488 stain may optimally be visualized using charge‐coupled device/xenon arc lamp‐based imaging systems or 470–488 nm laser‐based gel scanners.
Journal ArticleDOI
Synthesis and photophysical properties of new fluorinated benzo[c]xanthene dyes as intracellular pH indicators.
TL;DR: Two new fluorinated benzo[c]xanthene dyes were synthesized by reaction of fluorinated 1,6-dihydroxynaphthalenes with 2,4- (and 2,5)-dicarboxy-3'-dimethylamino-2'-hydroxybenzophenone and their cell-permeable esters have been prepared for intracellular applications.