W
Walter Colli
Researcher at University of São Paulo
Publications - 137
Citations - 5353
Walter Colli is an academic researcher from University of São Paulo. The author has contributed to research in topics: Trypanosoma cruzi & Glycoprotein. The author has an hindex of 43, co-authored 137 publications receiving 5108 citations. Previous affiliations of Walter Colli include Oswaldo Cruz Foundation & Federal University of São Paulo.
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Journal ArticleDOI
Adhesion and interiorization of Trypanosoma cruzi in mammalian cells.
Norma W. Andrews,Walter Colli +1 more
TL;DR: Both adhesion and interiorization were found to be proportional to the time of exposure of cells to parasites and to the multiplicity of infection, and effects that can be reversed by trypsinization of the parasites prior to exposure of the cells were found.
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Galactofuranose-containing glycoconjugates in trypanosomatids
TL;DR: The metabolic pathways involved in the attachment to or removal of galactofuranose from glycoconjugates have not yet been elucidated and this is an area of incipient research, but of growing importance, since it will foster the design of inhibitors which may prove to be useful for the treatment of disease.
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Trypanosoma cruzi: parasite shed vesicles increase heart parasitism and generate an intense inflammatory response.
Ana Claudia Torrecilhas,Renata Rosito Tonelli,Wander Rogério Pavanelli,João Santana da Silva,Robert I. Schumacher,Wanderley de Souza,Narcisa L. Cunha e Silva,Ises de Almeida Abrahamsohn,Walter Colli,Maria Júlia Manso Alves +9 more
TL;DR: Results indicate that T. cruzi shed membrane components increase tissue parasitism and inflammation by stimulation of IL-4 and IL-10 synthesis and thus may play a central role in the pathogenesis of Chagas' disease acute phase.
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In vitro selection of RNA aptamers that bind to cell adhesion receptors of Trypanosoma cruzi and inhibit cell invasion.
TL;DR: The SELEX technique was used to evolve nuclease-resistant RNA ligands (aptamer = to fit) that bind with affinities of 40-400 nm to parasite receptors for the host cell matrix molecules laminin, fibronectin, thrombospondin, and heparan sulfate.
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Trypanosoma cruzi: Shedding of surface antigens as membrane vesicles
M F Goncalves,Eufrosina Setsu Umezawa,Alejandro M. Katzin,Wanderley de Souza,Maria Júlia Manso Alves,Bianca Zingales,Walter Colli +6 more
TL;DR: Biochemical and electron microscopic data strongly suggest that most of the surface antigens from tissue culture-derived trypomastigotes from Trypanosoma cruzi are released as plasma membrane vesicles, ranging from 20 to 80 nm in diameter.