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Wan-Sung Choi

Researcher at Gyeongsang National University

Publications -  6
Citations -  117

Wan-Sung Choi is an academic researcher from Gyeongsang National University. The author has contributed to research in topics: ASK1 & MAP kinase kinase kinase. The author has an hindex of 6, co-authored 6 publications receiving 111 citations.

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Proteomic analysis reveals an elevated expression of heat shock protein 27 in preeclamptic placentas.

TL;DR: The study confirmed that four proteins are upregulated and eight proteins are downregulated in preeclampsia, including signal transduction protein and molecular chaperon protein, in which Hsp27 is upregulated.
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Expression of clusterin in normal and preeclamptic placentas.

TL;DR: Clusterin is a multifunctional protein that is up‐regulated during many different pathophysiological states and may be related to a compensation mechanism involving aggregation of soluble proteins, inhibition of complement‐mediated cell damage, adaptive regeneration or apoptosis.
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Increased interaction between heat shock protein 27 and mitogen-activated protein kinase (p38 and extracellular signal-regulated kinase) in pre-eclamptic placentas.

TL;DR: Evaluated the interaction between Hsp27 and mitogen‐activated protein kinase (MAPK) (p38, extracellular signal‐regulated kinase [ERK], and c‐Jun N‐terminal kinase) in the human placenta derived from patients with pre‐eclampsia.
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Increased NFAT5 expression stimulates transcription of Hsp70 in preeclamptic placentas

TL;DR: HIF-1α positively regulates the induction of NFAT5 and Hsp70 by placental hypoxia andNFAT5 stimulates transcription of Hsp 70 in response to placentalhypoxia in models of human placental Hypoxia models in vitro.
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PKC δ in Preeclamptic Placentas Promotes Bax Dissociation from 14-3-3 ζ through 14-3-3 ζ Phosphorylation

TL;DR: Preeclampsia is associated with higher levels of cleaved caspase-3, Bax, 14-3-3 zeta, phospho-(Ser)-14-3 -3, and PKC delta, which may at least in part explain the apoptosis-inducing activity of PKCDelta.