Weihua Cui

TL;DR: It is indicated that Flt3L can increase the resistance of mice to a P. aeruginosa burn wound infection through both stimulation of dendritic cell production and enhancement of dendedritic cell function.

TL;DR: It is concluded that DCs play an important role in the acceleration of early wound healing events, likely by secreting factors that trigger the proliferation of cells that mediate wound healing.

TL;DR: It is found that inhibition of bacterial H2S production can increase the susceptibility of both bacterial species to rapid killing by immune cells and can improve bacterial clearance after severe burn, an injury that increases susceptibility to opportunistic infections.

TL;DR: Test the hypothesis that Flt3L administration after burn injury decreases susceptibility to wound infections by enhancing global immune cell activation and suggests that dendritic cell enhancement by FlT3L treatments after burn injuries protects against opportunistic infections through promotion of local and systemic immune responses to infection.

TL;DR: Induction of LPS tolerance enhanced systemic clearance of Pseudomonas aeruginosa and that this effect was augmented by neutralization of IL-10, which reversed the endotoxin-tolerant state.