Weiqing Han

TL;DR: The genome reveals that NG80-2 is well equipped for adaptation into a wide variety of environmental niches, including oil reservoirs, by possessing genes for utilization of a broad range of energy sources, genes encoding various transporters for efficient nutrient uptake and detoxification, and genes for a flexible respiration system.

TL;DR: A chemical approach was presented which enabled reconstitution of the E. coli O-polysaccharide biosynthesis pathway in vitro, providing a well-defined system for further underpinning molecular details of this biosynthetic pathway.

TL;DR: An approach that combines arrays of reactions on an immobilized array of acceptors with analysis by mass spectrometry to screen putative GTs is described, providing a label-free method for the rapid functional annotation of putative enzymes.

TL;DR: The present work represents an in vitro systematic investigation of the WaaL function using a chemical biology approach, providing a system that could facilitate the elucidation of the mechanism of WAAL-catalyzed ligation reaction.

TL;DR: A DNA microarray targeting O-serotype-specific genes was developed and shown to be specific and reproducible for serotyping Shigella and pathogenic E. coli and is promising for applications in basic microbiological research, clinical diagnosis, food safety, and epidemiological surveillance.