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Weiyu Luo
Researcher at Harbin Veterinary Research Institute
Publications - 2
Citations - 96
Weiyu Luo is an academic researcher from Harbin Veterinary Research Institute. The author has contributed to research in topics: Viral replication & Golgi apparatus. The author has an hindex of 2, co-authored 2 publications receiving 57 citations.
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Phospholipid scramblase 1 interacts with influenza A virus NP, impairing its nuclear import and thereby suppressing virus replication.
Weiyu Luo,Jie Zhang,Libin Liang,Guangwen Wang,Qibing Li,Pengyang Zhu,Yuan Zhou,Junping Li,Yuhui Zhao,Nan Sun,Shanyu Huang,Chenchen Zhou,Yu Chang,Pengfei Cui,Pucheng Chen,Yongping Jiang,Guohua Deng,Zhigao Bu,Chengjun Li,Li Jiang,Hualan Chen +20 more
TL;DR: It is found that the stable overexpression of PLSCR1 suppressed the nuclear import of NP, hindered the virus life cycle, and significantly inhibited the replication of various influenza subtypes.
Journal ArticleDOI
Host cellular protein TRAPPC6AΔ interacts with influenza A virus M2 protein and regulates viral propagation by modulating M2 trafficking
Pengyang Zhu,Libin Liang,Xinyuan Shao,Weiyu Luo,Shuitao Jiang,Qingqing Zhao,Nan Sun,Yuhui Zhao,Junping Li,Jinguang Wang,Yuan Zhou,Jie Zhang,Guangwen Wang,Li Jiang,Hualan Chen,Chengjun Li +15 more
TL;DR: The results indicated that TRAPPC6AΔ, through its interaction with M2, slows M2 trafficking to the apical plasma membrane, favors viral replication in vitro, and positively modulates virus virulence in mice.