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Will L. Goff
Researcher at United States Department of Agriculture
Publications - 55
Citations - 2121
Will L. Goff is an academic researcher from United States Department of Agriculture. The author has contributed to research in topics: Babesia bovis & Antigen. The author has an hindex of 29, co-authored 55 publications receiving 2028 citations. Previous affiliations of Will L. Goff include University of California, Davis & Washington State University.
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Common and isolate-restricted antigens of Anaplasma marginale detected with monoclonal antibodies.
TL;DR: Anaplasma marginale-infected erythrocytes were examined for the presence of maturation, isolate-restricted, and isolate-common antigens by indirect immunofluorescence with monoclonal antibodies, demonstrate antigenic heterogeneity among isolates of A. marginale and provide a method for the identification and isolation of common antigen for diagnostic tests.
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Detection of Babesia bovis carrier cattle by using polymerase chain reaction amplification of parasite DNA.
TL;DR: Characteristics of the apocytchrome b gene may make this a valuable target DNA for PCR-based detection of other hemoparasites, according to the results of a PCR test on carrier cattle infected with Babesia bovis.
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Immunization of cattle with a 36-kilodalton surface protein induces protection against homologous and heterologous Anaplasma marginale challenge.
TL;DR: The potential of AmF36 as a subunit immunogen for bovine anaplasmosis is demonstrated and a structural basis for its cross-protective ability is indicated.
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Immune control of Babesia bovis infection
TL;DR: The innate and acquired immune mechanisms that define resistance in young calves and correlate with the development of concomitant immunity in older cattle following recovery from clinical disease are described.
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Identification of Babesia bovis merozoite surface antigens by using immune bovine sera and monoclonal antibodies.
Will L. Goff,William C. Davis,Guy H. Palmer,Terry F. McElwain,Wendell C. Johnson,J F Bailey,T.C. McGuire +6 more
TL;DR: Three Babesia bovis merozoite surface proteins with relative molecular weights were identified by indirect immunofluorescence of livemerozoites and by immunoprecipitation of 125I-surface-labeled merozosite proteins with immune bovine sera and monoclonal antibodies, and these proteins were clearly of parasite origin.